Association of Risk Factors For Diabetes Mellitus and Serum Electrolytes
Journal Title: Journal of Indus Medical College - Year 2019, Vol 2, Issue 2
Abstract
OBJECTIVE: The purpose of the study was to examine the imbalance of selected serum electrolytes and the associated factors in diabetic patients. METHODOLOGY: This was a cross-sectional study, carried out in diabetic patients attending their follow-up appointments at the Polyclinic Hospital Islamabad. To include 155 patients with diabetes mellitus in the study, a convenience technique of sampling was used. A questionnaire was utilized to comprise all necessary information from each patient with diabetes mellitus. 5mL of venous whole blood was extracted from each participant and ion-selective electrode (ISE) device and automated chemistry analyzer were processed and tested for determination of serum electrolyte and serum glucose respectively. In order to determine the association and meaningful link between irregular electrolytes in serum and independent parameters, the model of Pearson's correlation coefficient and regression for multivariate logistic were performed respectively. RESULTS: In diabetic patients, an increased prevalence rate of disturb electrolytes in the serum was prominent. The total prevalence rate was 45.80% (n=71/155), with hyponatraemia being the largest (46.47%), followed by hypochloraemia and hypercalcaemia (19.48% and 14.28% respectively. There were strong positive associations between type of medication, age and high body mass index (BMI) and elevated serum concentrations of sodium (Na+) (r=0.712, P=0.003), potassium (K+) (r=0.817, P=0.002) and chloride (Cl-) (r=0.518, P=0.003). In diabetic patients, risk factors for serum electrolyte disorders were statistically defined as being employed (AOR: 3.879, 95%, P-value: (0.044), treated with various drugs (AOR: 2.988, 95% C.I, P value: 0.012) and not able to regulate the level of blood glucose or increased level of glucose (hyperglycaemic) (AOR: 3.18, 95% C.I, P value: <0.001). CONCLUSION: In patients with diabetes mellitus, the concentration of serum electrolyte was abnormal significantly. In advanced patients of diabetes mellitus, incidence of imbalanced concentrations was more prevalent, with some parameters had a clear strong association with deranged electrolytes in the serum in patients with diabetes mellitus.
Authors and Affiliations
Sher Ali, Arshad Ali Lakho, Shahzad Ali Jiskani, Halar Rahim, Ashraf Ali
Keywords
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