Comparative Study between Intravenous Thiopentone Sodium and Propofol on the Recovery Profile of the Patients after Electroconvulsive Therapy
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 4
Abstract
Abstract Introduction: The use of electroconvulsive therapy (ECT) to induce a generalized epileptic seizure was first described in 1938 and was performed without anesthesia for almost 30 years. Modification of treatment process, improvement in the anesthetic management, and greater attention to the preparation for emergencies have resulted in a high level of safety for ECT and its acceptance as a treatment in psychiatry. Objectives: Objectives of the study were to study the recovery profile after electroshock in patients undergoing ECT with intravenous thiopentone sodium versus propofol. Materials and Methods: This study was conducted on psychiatric patients (18-45 years), who belonged to the American Society of Anesthesiologists Grade I or II, and were already on medication. Each patient underwent a series of prescribed ECT. In this study, two treatment groups were included: ECT with thiopentone sodium (Group A) and ECT with propofol (Group B), as induction agents. A total 60 cases were included in the study. Un-paired t-test was applied for the analysis. Results: No significant difference in the baseline value of oxygen saturation between the two groups. Duration of apnea was more in the propofol group; statistically not significant (P > 0.5). In the recovery profile, time taken for spontaneous eye opening was less in the propofol group; statistically not significant (P > 0.5). Time taken for verbal communication and phonation; for orientation of patient to name, place, and time; for patients sitting with support and sitting without support was less in the propofol group; statistically significant (P < 0.05). Mean sedation score was 2.40 with the thiopentone sodium group as against only 1.07 with the propofol group, and this difference was statistically significant. Conclusions: Propofol was superior to thiopentone sodium with respect to recovery and side effects after ECT.
Authors and Affiliations
Santosh N Bodkhe, Roshan M Shende, Pankaj R Bhople, Sonal Agrawal
Keywords
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