Familial Lichen Palnus and Genetic Influence: A Brief Commentary
Journal Title: International Journal of Contemporary Medicine surgery and Radiology - Year 2016, Vol 1, Issue 1
Abstract
Lichen planus (LP), considered primarily an immune mediated disorder has unknown aetiology, though there are several hypothesis proposed like genetic, infectious, oxidative stress, psychogenic, autoimmune factors etc. There have been multiple reports of LP in two or more of the family members related by blood, known as familial LP, along with evidences of certain human leukocyte antigens (HLA) in LP patients who were either related or non-related. Based on these reports a genetic aetiology of LP has been proposed. Inspite of these reports, the data available does not provide very strong evidence. This review runs a brief commentary on genetical aspects of lichen planus.
Authors and Affiliations
Nisheeth Saawarn, Swati Saawarn, MC Shashikant, Pinakapani R, Nidhi Dhakar, Raju Ragavendra T
Keywords
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- EP ID EP423141
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