Genetic pheochromocytoma/paraganglioma– A review

Journal Title: Scientific Journal of Medical Science - Year 2013, Vol 2, Issue 11

Abstract

The prevalence of pheochromcytoma in hypertensive patients is less than 1%.Most PHEOs occur sporadically, but a substantial proportionmay be associated with germ line mutations of genes predisposing to thedevelopment of familial syndromes like multiple endocrineneoplasia(MEN),Von-Hippel Lindau(VHL) disease,neurofibromatosis type 1(NF-1),familial paraganglioma/pheochromocytoma (PGL/PHEO) related to geneticmutation encoding the mitochondrial protein succinate dehdrogenase sub units(SDH-BCD) .Screening for genetic mutation is imperative as it may add more onmanagement and surveillance of this patients .This review summarize therelevant data related to this fascinating clinical entity.

Authors and Affiliations

F. B. Pambinezhuth| National Diabetes and Endocrine center –Royal hospital, Muscat Oman.

Keywords

Related Articles

Assessment of essential trace metals (iron, copper and selenium) and heavy metal (lead) in obese diabetics (type 2 diabetic) patients

ABSTRACT Background: It is evident that the metabolism of some trace metals is altered in diabetes mellitus and these micronutrients may have specific roles in the pathogenesis and progression of the disease. The aim of...

Neck incision for comprehensive neck dissection

Over decades, a variety of incisions have been described for neck dissections. The current practice for neck dissection is to employ only a transverse incision along a suitable skin crease. We attempted a modification o...

GH and IGF-1 responses of elite boxers and field hockey players to increasing maximal aerobic exercise

Objection: To evaluate the response of some metabolic factors in elite sportsmen performing individual (boxing) and team (Field hockey) sports who apply different training models to the increasing maximal aerobic exercis...

The study of effect of aqueous Cucurbita pepo linn seed extract on serum prolactin level of lactating female albino rats

Prolactin participation has been established for a growing number of physiological actions of these, the best studied is the stimulation of mammary gland development and induction of milk synthesis at the end of pregnanc...

Ovarian hyperstimulation syndrome (OHSS) in spontaneous pregnancy

It has been known that most cases of ovarianhyperstimulation syndrome (OHSS) are almost exclusively associated withcontrolled ovarian stimulation with gonadotrophins or occasionally, clomiphenecitrate. However, OHSS is a...

Download PDF file
  • EP ID EP1251
  • DOI 10.14196/sjms.v2.i11.1023
  • Views 489
  • Downloads 29

How To Cite

F. B. Pambinezhuth (2013). Genetic pheochromocytoma/paraganglioma– A review. Scientific Journal of Medical Science, 2(11), 208-211. https://www.europub.co.uk/articles/-A-1251