Information technology and hardware-software complex for monitoring the state of biological fluid samples
Journal Title: Вісник Житомирського державного технологічного університету. Серія: Технічні науки - Year 2018, Vol 81, Issue 1
Abstract
The article deals with the development of information technology for monitoring and diagnostics of the state of liquid biological samples. The method is proposed on the basis of factor analysis caused by an information electric signal as a result of mechanical action on a biological sample. The paper provides a detailed analysis of the methods using a similar (piezoelectric) effect in medical and research practice. The aim of the work was the development and experimental study of the method and systems for monitoring the state of liquid biological samples. The basic models are used as the informational model of the factorial influence i.e. parametric and the model of dispersion components. The level of mechanical action on the liquid sample is used as the levels of the influencing factor in this method, and the potential difference from the electrodes immersed in the liquid sample was used as an informative signal. The paper shows the structural diagram of a laboratory installation and describes the principle of its operation. For experimental verification of the developed method, 10 samples of whole blood of patients (5 without pathology, 5 with colorectal cancer) were used in the work. The robot provides a technique for preparing the data obtained and provides an information technology for identifying informative features. With the use of the described informative models of factorial influence, an informative analysis of the proposed parameters and an estimation of the quantitative content of control information in them are presented. As a result of the experimental study, it was concluded that the developed information technology makes it possible to detect changes in the state of the controlled biochemical material with 95 % certainty.
Authors and Affiliations
P. F. Shchapov, R. S. Tomashevskіy
Keywords
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