Is there a difference in 25-hydroxyvitamin D levels between female university students with and without joint hypermobility?
Journal Title: The European Research Journal - Year 2019, Vol 5, Issue 4
Abstract
Objectives: Individuals with joint hypermobility (JH) constitute a sensitive group with regard to musculoskeletal problems. This study aimed to investigate whether females with generalized joint hypermobility (GJH) are at risk of hypovitaminosis D compared with non-GJH female participants and whether there is a relationship between vitamin D levels, Beighton score and musculoskeletal complaints. Methods: In this cross-sectional, descriptive and case-control study, 76 female participants aged 18-25 years were included. The Beighton score with a cut-off of 4/9 was applied for defining GJH. In addition, serum biochemical (the enzymatic colorimetric method) and hormonal (the electrochemiluminescence method) parameters were evaluated. Results: The mean serum 25-hydroxyvitamin D (25[OH]D) levels of GJH (n = 38) and non-GJH (n = 38) groups were 15.70 ± 7.96 ng/mL and 16.80 ± 5.45 ng/mL, respectively. There was no statistically significant difference between the groups in terms of biochemical and hormonal parameters. We found vitamin D deficiency in 89.5% of participants with GJH, and 84.2% of controls. There was no correlation between vitamin D, Brighton criteria, and musculoskeletal complaints. Conclusion: The female participants with GJH showed similar frequency of musculoskeletal complaints and similar low level of 25(OH)D in relation to controls.
Authors and Affiliations
Filiz Tuna, Hande Özdemir, Derya Demirbağ Kabayel, Zeynep Banu Doğanlar
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