RETROSPECTIVE ANALYSIS OF 43 CASES OF INTRACRANIAL TUBERCULOSIS USING MR IMAGING
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 81
Abstract
BACKGROUND Intracranial tuberculosis has varied presentation and if not treated early can lead to devastating clinical outcome. This study aimed at retrospectively analysing the varied forms of presentation of intracranial tuberculosis and its associated complications in our hospital setup. MATERIALS AND METHODS It is a descriptive type of study in which the MRI scans of 43 cases with intracranial tuberculosis, which were done in the Department of Radiodiagnosis, Assam Medical College, Dibrugarh, India, were retrospectively analysed. The study population comprised of 11 children and 32 adults with ages ranging from 11 to 60 yrs. (mean age, 26.58 yrs.). MR imaging was done by 1.5 Tesla machine using conventional spin echo sequences and additional sequences such as MR Spectroscopy and Diffusion-weighted Imaging. RESULTS It was found in this study that majority of cases of intracranial tuberculosis were in the age group of 11-20 yrs. (44.2%). The most frequent tuberculous lesions encountered were tuberculomas (79.1%) followed by tubercular meningitis (72.1%), cerebritis (6.9%) and abscesses (4.6%). Tuberculomas were frequently located in cerebral hemispheres (88.2%) followed by cerebellar hemispheres (61.7%), brainstem (26.5%) and basal ganglia (8.8%). Tubercular Meningitis-induced infarcts were most commonly located in basal ganglia (73.3%) followed by thalamus (33.3%), brainstem (33.3%), frontal lobe (33.3%), internal capsule (26.7%), cerebellar hemisphere (26.7%), corpus callosum (20%), parietal lobe (6.7%) and external capsule (6.7%). In adults, the most frequent lesions encountered in decreasing order of frequency were tuberculomas (81.25%), tubercular meningitis (78.1%), infarcts (31.25%), cerebritis (9.37%), abscess (6.3%), ependymitis (6.25%) and choroid plexitis (3.1%). In children, the most frequent tuberculous lesions encountered were tuberculomas (72.7%) followed by tubercular meningitis (54.5%) and ependymitis (9.0%). CONCLUSION MRI plays an important role in the diagnosis of intracranial tuberculosis and its associated complications. It helps in identifying the extent of involvement and differentiating tuberculous lesions from other pathologies.
Authors and Affiliations
Liter Nguri, Pronami Borah, Rudra Kanta Gogoi
Keywords
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- EP ID EP275337
- DOI 10.14260/jemds/2017/1233
- Views 97
- Downloads 0
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