3D Printing of Pharmaceutical Drug Delivery Systems
Journal Title: Archives of Organic and Inorganic Chemical Sciences - Year 2018, Vol 1, Issue 2
Abstract
Drug delivery refers to approaches, systems, technologies and formulations for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect. The concept of drug delivery has greatly evolved over the years from immediate-release oral dosage forms to targeted-release drug delivery systems. Indeed, the necessity of controlling the drug release profile to modulate the absorption, the distribution, the metabolization and the elimination of the drug rapidly appeared as a key factor for improving product efficacy and safety as well as to increase the compliance of the patients [1]. In the drug delivery area, versatile therapeutic systems intended to yield customized combinations of drugs, drug doses and release kinetics have drawn increasing attention, especially because of the advantages that personalized pharmaceutical treatments would offer [2]. Three dimensional printing (3DP) technology is a novel technique for rapid prototyping, which constructs solid objects by deposition of several layers in sequence. The introduction and application of 3D printing have promoted enormous innovations in many diverse fields, including aerospace industry, architecture, tissue engineer, biomedical research and pharmacy. It seems that 3D printing technology will lead a new epoch of the next industrial revolution based on its versatility and diversity. Along with development and progress in science and technology, the 3D printing technology gets mature enough so that anyone can apply it with open-source software at a relative lower material cost [3]. The recent introduction of the first FDA approved 3D-printed drug has fuelled interest in 3D printing technology, which is set to revolutionize healthcare. Since its initial use, this rapid prototyping (RP) technology has evolved to such an extent that it is currently being used in a wide range of applications including in tissue engineering, dentistry, construction, automotive and aerospace. However, in the pharmaceutical industry this technology is still in its infancy and it's potential yet to be fully explored [4].
Authors and Affiliations
Diogo José Horst
Keywords
Related Articles
- EP ID EP576750
- DOI 10.32474/AOICS.2018.01.000109
- Views 100
- Downloads 0
Straw Based Biorefinery
n India energy security and exploring the production of valuable chemicals , which are otherwise mostly imported have become imperative necessity The advantage of abundant availability of paddy and its straws, specifical...
Novel Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Clindamycin and Adapalene in Pharmaceutical Dosage Forms
A simple, accurate, rapid and precise isocratic stability indicating reversed-phase high-performance liquid chromatographic method has been developed and validated for simultaneous determination of Clindamycin...
The Carbonyl Groups as Scaffolds in Coordination Chemistry
Carbonyl compounds are of paramount importance in the formation of C-C bonds and metal-ion control of their reactivity offers a way to promote, inhibit, or control such reactions [1]. The co...
Si-Psa Tape with the Addition of Dolomite
It is well known that tapes on the silicone pressure-sensitive adhesives base are high quality products used for special applications. Due to the excellent performance characteristics such as high adhesion, cohesion and...
Synthesis and Antitubercular Acitivity of New Imidazo [2,1-B] [1,3,4] Thiadiazole-Phenothiazine Derivatives
New series of 10-(2-Styryl-5,6-dihydro-imidazo[2,1-b] [1,3,4] thiadiazole-6-yl)-10H-phenothiazine were synthesized by cyclisation of various carboxylic acid with thiosemicarbazide in presence of sulphuric acid was to get...