A Case of Age Related Macular Degeneration Responding to a Statin – Perspective for a New Treatment
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 10, Issue 2
Abstract
The newly started use of atorvastatin eliminated the need for further intravitreal injections of ranibizumab for 37 months in a case of wet form of age related macular degeneration(AMD). Repeated optical coherence tomographic examinations documented the absence of intra- or subretinal fluid. The known effects of statins on endothelial function might also improve retinal capillary endothelial function and reduce or eliminate fluid leakage into the intra- or subretinal space. This would intervene earlier in one important disease mechanism of AMD than the injection of anti-VEGF therapies. A randomized study is necessary to prove this hypothesis.
Authors and Affiliations
Helmut Gohlke, Lutz L. Hansen
Keywords
Related Articles
- EP ID EP348458
- DOI 10.9734/BJMMR/2015/19135
- Views 106
- Downloads 0
Geneneralised Idiopathic Acanthosis Nigricans- A Severe Presentation in a Nigerian Girl
Acanthosis nigricans is characterized by hyperpigmented and velvety verrucous plaques observed as symmetric eruptions. We report a 22 year old girl with generalized idiopathic acanthosis nigricans with no family history,...
Sickle Cell Disease in Pregnancy: Maternal and Fetal Outcome in Port Harcourt, Nigeria
Background: Medical experts for many years have daunted the occurrence of pregnancy in homozygote sickle cell patients. This is because of associated high risk for mother and fetus. The aim of this study is to determine...
Gastrointestinal Stromal Tumors: Experience from a Single Surgical Unit
Background: Gastrointestinal stromal tumors (GISTs) are rare tumors, but comprise the most common mesenchymal neoplasms of the gastrointestinal (GI) tract. We report a clinical series of abdominal GIST and discuss the d...
Assessment of Relation between Recurrence of Enterocutaneous Fistula and Preoperative C-reactive Protein Level after Complete Surgical Repair
Background: Recurrence of enterocutaneous fistula after the definite surgical repair has not changed significantly. In postoperative complication of abdominal surgery, serum C-reactive protein level is used for evaluatio...
Association between Helicobacter pylori Infection, ABO Blood Groups and Rhesus Factor in Peptic Ulcer Disease Patients, in Gezira, Central Sudan
Blood group antigens were associated with peptic ulcer disease, which is potentially caused by Helicobacter pylori. It was recently demonstrated that the receptor for H. pylori is the blood group antigen lewisb, which is...