A Comparative Acute Anti-Inflammatory Activity Of Kashaya(Aqueous Extract) Prepared From Leaves, Roots And Stem Barks Of Bruhatpanchamoola (A Group Of Five Perennial Plants)
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2018, Vol 8, Issue 5
Abstract
The present study was carried out to evaluate and compare anti-inflammatory activity of Leaves, Roots and Stem Barks of Brihatpanchamoola (A Group of Five Perennial Plants) in kashaya (Aqueous Extract). Bruhatpanchmoola is a formulation of five perennial plants roots i.e. Bilva {Aegle marmelos (L.) Corr.}, Gambhari (Gmelina arborea(L).), Agnimanth (Clerodendrum phlomoidisL.f.), Shyonaka {Oroxylum indicum(L.) Vent.} and Patla {Stereospermum suaveolens(Roxb.) DC.}.Kashaya prepared by Leaves, root and stem bark of Brihatpanchamoola in Carrageenan induced paw edema model. Wister strain albino rats of either sex were selected and divided in to twenty groups of 6 animals each. The test drug was administered orally at a dose of 0.86 ml/200 gm body weight of rat. Ibuprofen was used as standard anti-inflammatory drug for comparison. The study result shows that Bilwa root can be substituted by stem bark but not with leaf. Agnimanth root cannot be substituted by Stem bark & leaves. Patala root can be substituted by stem bark but not with leaf. Shyonak root cannot be substituted by Stem bark & leaves. Gambhari root can be substituted by stem bark but not with leaf. In combination Root combination can be substituted by Stem bark combination but not with leaves combination of all plants. Bilwa stem or bilwa root or Gmabhari root or Gambhari stem can be in the place of combination of all plants Sterm bark or Roots.
Authors and Affiliations
Mr. Ajit Lingayat, Dr. M. B. Patil2, Dr. B. Shreenivasa Prasad3
Keywords
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