A Comparative Evaluation of Dexmedetomidine And Clonidine As An Adjunct With Inj. Levobupivacaine For Thoracic Epidural Anaesthesia in Open Cholecystectomy
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 12
Abstract
Background: Clonidine and Dexmedetomidine are alpha 2 adrenergic agonists when used intrathecally with local anesthetics, they are known to potentiate the action of local anesthetics as well as have analgesic properties.we use both the drugs in thoracic epidural anaesthesia with Levobupivacaine. Aim: To find better adjuvant in regional anesthesia comparing efficacy and clinical profile of alpha 2 adrenergic agonists Clonidine and Dexmedetomidine with special emphasis on the following parameters 1. Hemodynamic stability and sedative property 2. Onset and duration of sensory and motor block 3. Ability to provide smooth intraoperative and post operative analgesia. Methods: 50 patients of ASA grade I and II, scheduled for elective cholecystectomy at our institute satisfying inclusion criteria were selected and divided randomly into two groups C and D. Hemodynamic parameters, onset and duration of sensory block and motor block, duration of epidural anesthesia and sedation scores recorded. Results: Sensory and motor block times were significantly longer in group D than Group C. The mean duration of sensory block was 205.2 (±25.87) min. in group C and 261.6 (±32.71) min. in group D and mean recovery time of motor block was 251.4 (±40.44) min. in group C and 322.2 (±24.60) in group D. Patient of group D had significantly less and delayed requirement of rescue analgesic i.e. mean duration of epidural anesthesia is 378.6 (±75.49) min. in group C and 492 (±49.99) min. in group D. Conclusion: Epidural Dexmedetomidine with isobaric Levobupivacaine significantly prolongs sensory and motor block and post operative analgesia as compared to Clonidine.
Authors and Affiliations
Dr. Subhash ranjan das, Dr. Tushar H. Majumder, Dr. Chirashree chowdhury, Dr. Biswajit chakraborty
Keywords
Related Articles
- EP ID EP251459
- DOI 10.9790/0853-1612093237
- Views 122
- Downloads 0
Prevalence of Thyroid Disorders in Patients in Tertiary Care in South India: A Prospective Study
Iodine is an important micro-nutrient required for human nutrition. Iodine deficiency disorders (IDDs) are one of the major worldwide public health problems of today which causes wide spectrum of disabilities. It include...
The Ability of Root Canal Irrigant With Ethanol Extract of Lerak Fruit (Sapindus Rarak Dc) in Removing Root Canal Smear Layer (A Sem Study)
Application of root canal irrigant is one of the factors that affect the success of endodontic treatment. Unfortunately, there is no single irrigant which qualify as an ideal irrigant. Lerak fruit can be used as an alter...
To Evaluate the Success Rate and Future Outcomes of Laparoscopic Orchidopexy Compared With Open Orchidopexy in Modern Era"
INTRODUCTION- Isolated cryptorchidism is one of the most common congenital anomalies found at birth and affects about 3% of full-term male new-borns1-3 . Once cryptorchidism is diagnosed, treatment choices may include wa...
Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome; Case Report and Literature Review
Introduction: Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome is a rare congenital absence of uterus and the upper two-thirds of the vagina in women who have normal development of secondary sexual characteristics and norm...
A Rare Case of Lumbar Hernia – A Case Report
.