A Comparative Evaluation of Racemic Salbutamol and Levosalbutamol in Asthmatics
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2018, Vol 6, Issue 9
Abstract
Background: Asthma is a chronic respiratory disease. The present study was conducted to compare racemic Salbutamol and Levosalbutamol in patients with asthma. Materials & Methods: The present study was conducted on 180 patients of both genders (males- 88, females- 92). All were divided into 2 groups of 90 each. Group I received 0.63 mg levosalbutamol and group II received 2.5mg salbutamol. Respiratory rate (RR), Heart rate (HR) oxygen saturation in room air (SPO2), PEFR (peak expiratory flow rate) & Serum K+ levels were recorded initially and after giving 3 nebulizations at 20 min. Results: Mean age was 45.24± 4.8 and 42.06± 3.6 in group I and group II respectively. The difference was non- significant (P> 0.05). Pre treatment respiratory rate (RR) was 28.32 and 27.45 in group I and group II respectively. Heart rate was 110.25 and 106.34 in group I and group II respectively. SPO2 was 96.37 and 96.75 in group I and group II respectively. PEFR was 194.31 and 195.29 in group I and group II respectively. Serum K level was 4.87 and 4.81 in group I and group II respectively. Asthma score was 7.7 and 9.32 in group I and group II respectively. The difference was non- significant (P> 0.05). Post treatment respiratory rate (RR) was 25.4 and 26.81 in group I and group II respectively. Heart rate was 112.35 and 125.21 in group I and group II respectively. SPO2 was 98.11 and 98.82 in group I and group II respectively. PEFR was 267 and 265 in group I and group II respectively. Serum K level was 4.41 and 3.52 in group I and group II respectively. Asthma score was 5.3 and 6.9 in group I and group II respectively. The difference was significant (P< 0.05). Conclusion: It was found that PEFR, SPO2 and asthma score was better with Levosalbutamol as compared to racemic Salbutamol.
Authors and Affiliations
Vinay Sharma, Arshad Hasan
Keywords
Related Articles
- EP ID EP549216
- DOI -
- Views 128
- Downloads 0
Expression of Podoplanin in Odontogenic Keratocyst: An Immunohistochemical Study
Background: The odontogenic keratocyst (OKC) is known to have a more aggressive biologic behaviour than other cysts of jaw. Podoplanin which is frequently used as a lymphatic endothelial marker in OSCCs has recently been...
EVALUATION OF SENSORINEURAL HEARING LOSS IN HYPOTHYROIDISM
Background: The influence of the thyroid gland on hearing and the inner ear is one of the concerning factor in the area of medicine in today’s scenario. There are both clinical and laboratory evidences that hypothyroidis...
Evaluation of Complications in Uterus Surgery- A Clinical Study
Background: Worldwide hysterectomy is the most commonly performed major gynecological surgical procedure. The present study was conducted to assess the complications of uterus surgery. Materials & Methods: The present st...
LEFT VENTRICULAR DYSFUNCTION AFTER ACUTE MYOCARDIAL INFARCTION- A PROSPECTIVE STUDY
Background: Heart failure is an incessant complexity of myocardial localized necrosis. A few components, for example, recurrent myocardial ischemia, infarct size, ventricular remodeling, stunned myocardium, mechanical co...
Assessment of surface characteristics of two commercially available zirconia dental implant systems- A comparative study
Background: Dental implants have become a well-established treatment method for oral rehabilitation after tooth loss. In present study two zirconia implant system (Bredent white SKY™, Straumann pure Ceramic) were assesse...