A comparative study between systemic hypertension, intraocular tension and ocular perfusion pressure in primary open angle glaucoma, normal tension glaucoma and normal population in a tertiary care centre
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2018, Vol 4, Issue 1
Abstract
Introduction Glaucoma is a chronic progressive optic neuropathy characterized by retinal ganglion cell death and associated visual field loss irrespective of intraocular pressure changes The exact pathophysiological mechanism is not fully understood The vascular hypothesis of OAG states that a low blood pressure BP relative to IOP can lead to low mean ocular perfusion pressure MOPP thus impairing perfusion of the Optic Nerve Head ONH with resultant glaucomatous cupping and visual field lossObjective To find out any relationship between systemic hypertension intraocular tension IOP and mean ocular perfusion pressure MOPP in primary open angle glaucoma POAG normal tension glaucoma and normal populationMaterials and Methods It was a crosssectional observational study A total 125 patients attended in eye OPD at Calcutta National Medical College amp Hospital Kolkata in one year having primary open angle glaucoma including normal tension glaucoma Patients were distributed into three groups according to the technique of management Applanation Tonometry and fundoscopic evaluation 90 D lens were done for all cases Single recording of BP was taken Gonioscopy Humphreys central visual fields and pachymetry were done Data analyzed using standard statistical technique and a probability value lsquoprsquo value of lt 005 was considered as statistically significantResults The average age of the study population was 5438 plusmn892 years and ranging from 41 to 75 years The study was male preponderant The relationship between mean arterial pressure intraocular pressure and mean ocular perfusion pressure was statistically significant in all subgroupsConclusion There was a moderately strong correlation between MAP and MOPP whereas between MAP and IOP was weakly positive The relationship between IOP and MOPP was inversely correlatedKeywordsnbspOcular perfusion pressure Openangle glaucoma Systemic hypertension
Authors and Affiliations
Shashwat Bhattacharyya, Kumaresh Chandra Sarkar*, Ankit Shalikram Gedam
Keywords
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- EP ID EP474184
- DOI 10.18231/2395-1451.2018.0011
- Views 166
- Downloads 0
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