A Comparative Study of Equi-concentration of Bupivacaine-Fentanyl and Ropivacaine-Fentanyl for Epidural Labor Analgesia
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 6, Issue 5
Abstract
Introduction: Pain relief in labor has always been surrounded with myths and controversies and providing effective and safe analgesia during labor has remained an ongoing challenge. Neuraxial techniques were introduced for pain relief in labor in 1950. Modern neuraxial labor analgesia reflects a shift in obstetrical anesthesia, thinking away from a simple focus on pain relief toward a focus on the overall quality of analgesia. Aims and Objectives: The present study is carried out to compare equi-concentration of low dose (0.125%) bupivacaine-fentanyl 2 μg/mL and (0.125%) ropivacaine-fentanyl 2 μg/mL in primigravid full-term parturients for epidural labor analgesia. Materials and Methods: A prospective randomized double-blind controlled study was undertaken after obtaining Ethical Committee approval to compare the effect of equi-concentration of 0.125% bupivacaine with fentanyl 2 μg/mL and 0.125% ropivacaine with fentanyl 2 μg/mL in 60 parturients coming for delivery at Government Maternity Hospital, Hanamkonda. Results: This study was undertaken to compare equi-concentration of bupivacaine-fentanyl and ropivacaine-fentanyl for epidural labor analgesia in primigravida patients. Providing excellent labor analgesia, statistically significant motor blockade produced by bupivacaine compared to ropivacaine does not change mode of delivery at lower concentrations. Conclusion: In our study comparing equi-concentration (0.125%), bupivacaine-fentanyl 2 μg/mL and (0.125%) ropivacaine-fentanyl 2 μg/mL for epidural labor analgesia results indicate that both are equally effective clinically by intermittent epidural supplementation in providing excellent labor analgesia with hemodynamic stability, minimal motor blockade, mode of delivery, maternal satisfaction without serious maternal, or fetal side effects.
Authors and Affiliations
Gunda Shravan Kumar, B Srinivas Rao, U Mahesh Kumar
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