A COMPARATIVE STUDY OF LABOUR INDUCTION WITH INTRAVAGINAL MISOPROSTOL VERSUS INTRAVENOUS OXYTOCIN IN TERM PRELABOUR RUPTURE OF MEMBRANES
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 24
Abstract
BACKGROUND Management of Term Prelabour Rupture of Membranes (PROM) remains a matter of debate despite exhaustive research. Aims and Objectives- The objective of this study was to compare use of Tab. Misoprostol per vaginum versus Oxytocin infusion in PROM at term with respect to induction-delivery interval and maternal and foetal outcome. MATERIALS AND METHODS The present study was descriptive comparative study of Tab. Misoprostol (Group A) and Oxytocin infusion (Group B) for induction of labour in PROM at term. The study population consisted of 140 patients. RESULTS Mean induction delivery interval in present study was 541.06 ± 186 minutes in Group A and 556.69 + 219.54 minutes in Group B (p= 0.418), showing no significant difference between two groups. 8.6% women in Group A and 2.9% in Group B had hyperstimulation with no significant difference between the two. There was no significant difference in neonatal complications in the two groups. CONCLUSION The incidences of maternal and foetal untoward effects are similar with use of the two inducing agents with no significant difference in induction delivery interval. Vaginal administration of Misoprostol in a dose of 25 µg 6 hourly to maximum of four doses is an effective alternative of oxytocin for labour induction in term PROM, especially in low resource set-ups where storage facility for oxytocin and skilled staff for its titration is not available.
Authors and Affiliations
Sarika Arsekar, Manjusha Jindal
Keywords
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- EP ID EP450576
- DOI 10.14260/jemds/2018/650
- Views 113
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