A comparative study of serum magnesium in type 2 diabetes mellitus with and without retinopathy and healthy controls and its correlation with glycemic status
Journal Title: Journal of Oral Medicine, Oral Surgery, Oral Pathology and Oral Radiology - Year 2016, Vol 3, Issue 1
Abstract
Background: Type 2 diabetes mellitus(DM) is a disease of impaired carbohydrate metabolism. The onset of uncontrolled hyperglycemia causes various microvascular complications such as retinopathy and nephropathy. The present study aimed to see the effect of serum magnesium on glycemic control in the presence of retinopathy and to show their role in pathogenesis. Objectives: The study was designed to estimate and compare serum magnesium levels in cases of type 2 diabetes mellitus with and without retinopathy and healthy controls. A correlation of serum magnesium was done with glycosylated hemoglobin in diabetics with retinopathy and without retinopathy. Materials and methods: It was a case control study. The study included 60 cases of clinically diagnosed type 2 DM with retinopathy, 60 cases of type 2 DM without retinopathy and 60 matched healthy controls. Venous blood sample was analyzed for fasting blood sugar(FBS), post prandial blood sugar (PPBS), serum magnesium and glycosylated hemoglobin(HbA1c) in both cases and controls. Statistical analysis was done using student 't' test. Pearson's correlation was performed to establish the relationship between study variables. Results: There was significantly decreased levels of serum magnesium (p<0.001) in cases of retinopathy as compared to the controls. There was highly significant negative correlation between serum magnesium and glycosylated hemoglobin (HbA1c) in cases of DM with retinopathy. Conclusion: The severity of diabetic retinopathy in the study group was influenced by factors such as good glycemic control and hypomagnesemia. These parameters could be used as a supportive diagnostic tool in type 2 DM.
Authors and Affiliations
Arati Ganiger, K Mallikarjuna Swamy, Shivanand Gundalli, Rutuja Kolekar
Keywords
Related Articles
- EP ID EP241953
- DOI -
- Views 126
- Downloads 0
Verrucous Carcinoma of the Buccal Mucosa – A Case Report
Oral verrucous carcinoma (OVC) is a rare but well differentiated form of oral squamous cell carcinoma mainly seen in sixth or seventh decade of life with male predominance. Smokeless tobacco is found to be the most etiol...
Chronic osteomyelitis of maxilla: a rare case report
Osteomyelitis of the jaws is more common in developing countries and their treatment may be prolonged and difficult. Osteomyelitis is an acute or chronic inflammation involving both the cortical and trabecular aspects of...
Ameloblastic carcinoma of the mandible: A rare entity
Ameloblastic carcinoma (AC) is a very rare malignant odontogenic epithelial tumor of the jaws that has histological features of both ameloblastoma and carcinoma. It occurs primarily in the mandible in a wide range of age...
Bilateral Inferiorly Based Nasolabial Flaps for the Management of “Oral Submucous Fibrosisâ€: A Case Report
Oral Submucous fibrosis [OSMF] is the premaligmant condition in which patient suffers from limited mouth opening and fibrous bands over buccal mucosa. Various medical and surgical modalities are being suggested in the li...
Jaffe-Lichtenstein syndrome - Report of a rare case
Fibrous dysplasia FD is a benign slow growing skeletal disorder that causes swelling of the bone Lichtenstein described FD in 1938 as skeletal bone disorder which is distinguished by continuous replacement of normal bone...