A COMPARATIVE STUDY OF THE ANTIBACTERIAL ACTIVITY OF THE ETHANOLIC EXTRACTS OF PHLOGACANTHUS THYRSIFLORUS, HOTTUYNIA CORDATA, CURCUMA CAESIA AND SYZYGIUM JUMBOS
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 9
Abstract
The study was conducted to know and compare the antibacterial activity of the ethanolic extracts of Phlogacanthus thyrsiflorus (EEPT), Hottuynia cordata (EEHC), Curcuma caesia (EECC) and Syzygium jumbos (EESJ) on Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa by disc diffusion method. The ethanolic plant extracts were prepared from the bark of Syzygium jumbos and leaves of Phlogacanthus thyrsiflorus, Hottuynia cordata and Curcuma caesia by percolation method. Clinical isolates of Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa were obtained from the Department of Microbiology, Assam Medical College & Hospital. Disc diffusion method for antimicrobial susceptibility testing was performed according to the standard Kirby Bauer method. The whatmann-1 filter paper discs of 6mm sizes impregnated with the plant extracts were placed on Mueller-Hinton agar plates seeded with bacterial cultures of 0.5 Mc Farland standards. Ciprofloxacin (5μg/disc) was used as positive control. The antibacterial activities were assessed by the presence or absence of inhibition zones after incubating the plates at 370c for 24 hours. The ethanolic extracts of Phlogacanthus thyrsiflorus (EEPT) and Hottuynia cordata (EEHC) showed significant anti-bacterial activity against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. Ethanolic extracts of Syzygium jumbos (EESJ) showed significant activity against Staphylococcus aureus and Escherichia coli while ethanolic extracts of Curcuma caesia (EECC) showed significant anti-bacterial activity against Staphylococcus aureus. Maximum zones of inhibition to Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa were exhibited by Phlogacanthus thyrsiflorus, Syzygium jumbos and Phlogacanthus thyrsiflorus respectively.
Authors and Affiliations
Shagufa Ahmed , Mukundam Borah , Swarnamoni Das
Keywords
Related Articles
- EP ID EP98101
- DOI -
- Views 99
- Downloads 0
ROLE OF VARIOUS RISK FACTORS ASSOCIATED WITH CARDIOVASCULAR DISEASES
Coronary Artery Disease (CAD) is the leading cause of cardiovascular mortality world wide. Increasing rate of CAD mortality and projected rise in CAD mortality for 2020 in the developing world necessitates immediate pre...
A STUDY ON COMORBIDITIES AND LIFE STYLE ASSOCIATED WITH DIABETES PATIENTS
The present study focused on the co morbidities and lifestyle associated with diabetes patients. It was a non experimental prospective study and done in outpatient department of endocrinology, Amrita Institute of Medica...
TOXICOLOGICAL EVALUATION OF A MONOTERPENE ESTER, BORNYL PIPERATE FROM PIPER CHABA ROOT
Toxicological evaluation of bornyl piperate, a cytotoxic, antifungal and anti tubercular compound isolated from Piper chaba, was carried out on Swiss albino mice. After administration of the compound, blood and tissue sa...
SPECTROPHOTOMETRIC METHODS FOR SIMULTANEOUS ESTIMATION OF ATORVASTATIN AND NIACIN IN TABLET DOSAGE FORM
Two UV spectrophotometric methods were developed and validated for quantitative determination of atorvastatin (ATR) and niacin (NIA) in tablet dosage form. Method I is based on the simultaneous equation, and method II is...
EVALUATION OF HEAVY METALS IN ETHANOLIC LEAF EXTRACT OF ACACIA CATECHU AS INDICATOR OF POLLUTION BY ATOMIC ABSORPTION SPECTROPHOTOMETRIC (FAAS) ANALYSIS
Acacia catechu ethanolic leaf extract were selected to determine their heavy metals content and thereby to assure their safer therapeutic application. The trace and heavy metals were detected through atomic absorption sp...