A comparative study of the various patterns of oro-cutaneous fungi and their sensitivity to anti fungals between HIV patients and normal healthy individuals
Journal Title: Medical Journal Armed Forces - Year 2019, Vol 75, Issue 1
Abstract
Background: Dermatological diseases are the first recognized clinical manifestation Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS).1,2 The present study was undertaken to find out the clinical spectrum of the superficial mycoses, the etiological organisms and their drug sensitivity patterns among HIV positive patients and non HIV individuals attending the tertiary care hospital. Methods: The study population was 100 HIV patients and control patients were consecutive 100 HIV negative patients. Skin scrapings and swabs were obtained from the upper back, web spaces of toes, inguinal region, dorsum of tongue. All the samples were subjected to potassium hydroxide mount and stained with Calcoflour White and were cultured. The fungi were identified on the basis of colony and microscopic features in conjunction with results of physiologic evaluation by standard phenotypic identification criteria. Results: The total number of seropositive patients who had atleast one fungal infection was 57 and the total number of seronegative patients who had atleast one fungal infection was 21. In our study, fungal colonization was seen in 3.6% in clinically normal sites in retropositive patients and 1.6% in retronegatives. 76.59% in retropositive and 85.71% in retronegative patients the fungi cultured were sensitive to fluconazole. Conclusion: The findings of this study suggest that the skin of HIV patients may more frequently harbour common fungi even in the absence of visible clinical signs. Antifungal resistant fungi should be kept in mind while treating fungal infections.
Authors and Affiliations
P. Vijendran
Keywords
Related Articles
- EP ID EP665485
- DOI 10.1016/j.mjafi.2018.01.004
- Views 69
- Downloads 0
Are self-expandable metal stents superior to plastic stents in palliating malignant distal biliary strictures? A meta-analysis and systematic review
Background: Palliation for inoperable malignant distal biliary strictures can be achieved with self-expandable metal stents (SEMS) and plastic stents (PS). This is a meta-analysis to compare PS and SEMS. The aim of the s...
A qualitative study to develop an instrument for initial nurse assessment
Complex health care needs focus on accountability and necessity of inclusion of nurses in documenting and monitoring clinical care plans have brought in the concept of initial nurse assessment and nursing process. Howeve...
Physical examination: The dying art
When was the last time we as clinicians have performed a thorough physical examination on a patient who has walked into our clinic? The answer would surprise the best of clinicians amongst us. The problem is, we are not...
Loss of a guidewire
Central venous cannulation (CVC) is a common procedure being done in intensive care units (ICU) and operation rooms (OR). It is a safe procedure in the hands of well-trained professionals.
Rate of intrusion of maxillary incisors in Class II Div 1 malocclusion using skeletal anchorage device and Connecticut intrusion arch
Background: Nonsurgical correction of deep bite involves either extrusion of posterior teeth, intrusion of incisors, or combination of both. The introduction of skeletal anchorage device with microimplant provides near a...