A CORRELATIVE CYTOLOGICAL AND HISTOPATHOLOGICAL STUDY ON LESIONS OF THYROID GLAND
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 13
Abstract
BACKGROUND Thyroid gland is affected by a variety of pathological lesions. Fine needle aspiration cytology is a safe as well as cost effective tool in the study of thyroid lesions. Observations strongly support that Fine Needle Aspiration Cytology should be the initial investigation for thyroid disease. This study was conducted to find out the diagnostic ability of the FNAC (Fine Needle Aspiration Cytology) in detecting malignant neoplasm in comparison with histopathology. METHODS A diagnostic evaluation study was conducted in the Department of Pathology, Madurai Medical College, Madurai. A correlative study between Fine Needle Aspiration Cytology and histopathology was done for 117 cases. A range of cytological diagnosis was offered on all satisfactory smears. Finally, the results of FNAC and the histopathology were compared for all the 117 cases. RESULTS Sensitivity, specificity, positive predictive value (PPV), negative predictive value(NPV), and diagnostic accuracy for malignant lesions of thyroid were 58%, 98%, 85%, 92% and 91.45% respectively. Our study results were correlating with those of other studies. CONCLUSIONS Fine Needle Aspiration Cytology is a cost effective, simple, rapid, almost non-invasive, and an efficie
Authors and Affiliations
Sivaelagovan R, Malliga S, Veni Alagamuthu A.
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