A Decade of Invasive Candida Infection in Neonates: A Retrospective Study at a Tertiary Neonatal Intensive Care Unit in Thailand (2008–2018)
Journal Title: Vajira Medical Journal: Journal of Urban Medicine - Year 2024, Vol 68, Issue 2
Abstract
OBJECTIVE: To determine the epidemiology of invasive candida infection in the neonatal intensive care unit (NICU) at a tertiary care center in Thailand over 10 years. METHODS: A retrospective descriptive study was conducted. Participants were enrolled from all neonates diagnosed with invasive candidiasis infection (ICI) in Vajira Hospital between 2008 and 2018. Demographic data, microbiological results, and neonatal outcomes were reviewed. RESULTS: During the study period, 9,031 neonates were admitted to the NICU. A total of 14 neonates were diagnosed with ICI, giving a prevalence of 1.5 cases per 1,000 infants admitted to the level II and III NICU. The median (IQR) gestational age and birth weight were 28.5 weeks (27.0, 31.0) and 1,053 g (850.0, 1,586.5), respectively. In all, 10 (71.4%) and 8 (57.1%) neonates had positive blood and urine cultures, respectively. All infants had negative cerebrospinal fluid cultures. Among 14 neonates diagnosed with ICI, 7 (50.0%) neonates had positive cultures for Candida albicans. The overall mortality rate of neonates with ICI was 21.4%. CONCLUSION: ICI exhibits a low incidence rate within Vajira Hospital. This occurrence is demonstrably associated with prematurity, extremely low birth weight infants, and a demonstrably high mortality rate.
Authors and Affiliations
Pathaporn Prempraphan, Manisara Puengwongtrakul
Clinical Methicillin-Resistant Staphylococcus aureus May Transfer from Hospital to the Community Through Foods
Objective: To investigate the capability of methicillin-resistant Staphylococcus aureus (MRSA) and mecA-carrying Staphylococcus aureus (MCSA) transfer from hospital to community through foods due to the mecA gene is resp...
What is Diabetes Self-Management Education and Support?
Diabetes is a non-communicable disease that has become an epidemic in many countries around the world, with a significant increase in the number of cases. Patients are required to have good glycemic control and maintain...
Ruptured Pseudoaneurysm of Branch of Profunda Femoral Artery during Revision Total Hip Arthroplasty: a Case Report
A ruptured pseudoaneurysm is a rare but potentially fatal complication during revision total hip arthroplasty. We report a case of a 46-year-old female with a rupture of a pseudoaneurysm at the branch of the left profund...
Referral Time for Diabetic Retinopathy Screening and Impact on the Visual Acuity of Patients in a Tertiary Hospital
OBJECTIVE: To evaluate the referral time for the screening of diabetic retinopathy (DR) from the initial diagnosis of diabetes to retinal examination. We also compared visual results among groups screened at various dura...
Effects of Intensive Dietary Counseling versus Standard Dietary Counseling in Chronic Kidney Disease Patients: The Pilot Study
Background: Chronic kidney disease (CKD) is a major public health problem worldwide, particularly in Thailand. Several studies have recommended limiting protein and sodium intake with the benefit of delaying kidney deter...