A HISTOPATHOLOGICAL STUDY AND MDR -1 EXPRESSION IN GASTRIC CARCINOMA
Journal Title: PARIPEX-Indian Journal of Research - Year 2018, Vol 7, Issue 6
Abstract
Introduction : Gastric carcinoma is one of the common cause for cancer related mortality.There are three genes related to drug resistance,Multi drug resistance gene (MDR), Multi drug resistance Protein(MRP) and the lung resitance Protein (LRP). Material and Methods:30 gastrectomy specimens from surgical department received.5 microns thick section cut.Stained with hematoxyllin and Eosin (H &E), Immunohistochemical study carried out using MDR-1 antibodies. Conclusion: 18 out of 30 cases show positivity for MDR-1 gene expression.
Authors and Affiliations
Dr. S. Ramesh
Keywords
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