A HOSPITAL-BASED CASE-CONTROL STUDY ON IRON DEFICIENCY AND ANAEMIA IN CHRONIC HEART FAILURE WITH REDUCED EJECTION FRACTION
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 40
Abstract
BACKGROUND It has been found that patients with heart failure frequently have associated iron deficiency, which may or may not be associated with anaemia. Furthermore, it has been established that this iron deficiency is independently associated with exercise intolerance, poorer quality of life and increased mortality. The purpose of this study is to estimate the burden of iron deficiency and anaemia in patients who have heart failure with reduced ejection fraction. MATERIALS AND METHODS 50 patients with heart failure with reduced ejection fraction (EF < 40%) were compared with 50 age-matched controls who had no evidence of heart failure on history and clinical examination. All patients were investigated to identify iron deficiency and anaemia. RESULTS The prevalence of iron deficiency was 72% among cases and 36% among controls (P-value < 0.05). The prevalence of anaemia was 54% among cases and 28% among controls (P-value < 0.05). Patients with heart failure were 4.63 (95% CI 1.92 - 11.17) times more likely to be iron deficient and 3.21 (95% CI 1.26 - 8.21) times more likely to be anaemic compared with normal controls. CONCLUSION This study showed that there is a large burden of iron deficiency and anaemia in patients with heart failure with reduced ejection fraction. In view of the randomised controlled trials that have demonstrated benefit in correction of this iron deficiency, it may be prudent to assess and use iron status as a therapeutic target in all patients with heart failure
Authors and Affiliations
S. Sivaram Kannan, Damodaran Dhanasekaran
Keywords
Related Articles
- EP ID EP548215
- DOI 10.14260/jemds/2018/971
- Views 85
- Downloads 0
A RANDOMIZED CLINICAL TRIAL COMPARING EFFICACY OF VITRECTOMY WITH INTRA VITREAL TRIAMCINOLONE ACETONIDE INJECTION AND SIMPLE VITRECTOMY IN PATIENTS WITH VITREOUS HAEMORRHAGE DUE TO PROLIFERATIVE DIABETIC RETINOPATHY
Proliferative diabetic retinopathy affects about 5-10%of the diabetic population. It is the advanced form of the disease due to ischemic changes and this indicates progression towards more devastating form ie;...
“STUDY OF LARGE BOWEL OBSTRUCTION IN ADULTS”
[b]AIM[/b]: To study the Incidence, Etiology, Clinical features, Investigations undertaken to arrive at Diagnosis, Treatment and Post-operative outcomes of large bowel obstruction in adults. [b]METHODS[/b]: Thi...
STUDY OF HYPONATREMIA IN PAEDIATRIC PATIENTS WITH ACUTE LOWER RESPIRATORY TRACT INFECTION
BACKGROUND Hyponatremia is one of the most common electrolyte abnormalities seen in paediatric intensive care unit. Common conditions associated with hyponatremia are pneumonia, acute meningitis, and Kawasaki disease. We...
AWARENESS AND PRACTICE OF CONTRACEPTIVE METHODS AMONG MEN- A STUDY
BACKGROUND Considerable gap exists between awareness and contraceptive use, which is more conspicuous in vasectomy. In a Government Hospital, tertiary health care centre where 6000 deliveries per year are taking place, t...
A STUDY OF ABDOMINAL SURGICAL EMERGENCIES IN GERIATRIC PATIENTS
BACKGROUND Emergency surgery is defined as non-elective surgery that is performed with the aim to prevent morbidity or fatal health consequences of a surgically treatable disease.1,2 Aims and Objectives- To study and a...