A Prospective Histopathological Study of Neoplastic Lesions of Breast in North West Rajasthan.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 3
Abstract
Background: Breast cancer is the most common cancer in the women in western world and the most common cause of death in women between 35-55 years.The aim of the study was to describe different histopathological lesions of breast in context with age, sex and mode of presentation, their incidence and prevalence in North West Rajasthan. Methods: The present histopathological study was conducted in Department of Pathology, SPMC, Bikaner. Clinical data was obtained from hospital record and requisition submitted along with tissue specimen received in the department. Tissue bits were routinely processed. Sample was stained with H&E stain. Specimens obtained from eligible study population were examined grossly as well as microscopically to assess type of various morphological patterns, variations and +/- of secondary changes. Histologic grading was done by Modified Bloom and Richardson score. Results: The mean age of patients was 39.1±17.8 years with 437(96.6%) females and 17 (3.7%) males. Majority of benign lesions were of Fibroadenoma (82.8%) followed by Gynaecomastia (6.7%). Most common type of malignant carcinoma was Infiltrating ductal carcinoma (IDC) (84.5%) followed by Ductal carcinoma in situ (DCIS) (9.7%). majority of IDC (91cases) had grade 2 followed by 8 cases had grade 1 and 2 cases had grade 3. Conclusion: This study shows the importance of diagnosing in-situ carcinomas and differentiating from invasive carcinomas. Staging of the malignant lesions is helpful in assessing the patient’s risk and tailor-made management can be provided in each case, which include local, regional and systemic management.
Authors and Affiliations
Megha Verma
Keywords
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