A Prospective, Randomized, Double blinded, Comparative Study of Clonidine and Tramadol for Control of Shivering under Spinal Anesthesia
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 8
Abstract
BACKGROUND: Shivering is a common complication of spinal anesthesia. We compared the efficacy of intravenous clonidine and tramadol for the treatment of shivering under spinal anesthesia. MATERIALS AND METHODS: In this prospective, randomised, double blinded, comparative study, 80 patients coming for lower abdominal and lower limb surgeries under spinal anesthesia were included. Patients were grouped into group C and group T who received clonidine 0.5mcg/kg and tramadol 0.5mg/kg respectively after the onset of shivering. Time of onset of shivering, cessation of shivering after administration of drug, vital signs and side effects were noted. RESULTS: Time of cessation of shivering was shorter in group C compared to group T (2.51±0.66minutes and mean time taken by Tramadol to control shivering was 4.82±0.90 min). Group C had more incidence of decrease in heart rate and blood pressure and higher sedation scores. Group T had higher incidence of nausea and vomiting. CONCLUSION: Our study concludes that both study drugs Clonidine and Tramadol are effective in controlling shivering under spinal anesthesia but clonidine took shorter time to achieve cessation of shivering compared to tramadol. There is a significant improvement in SPO2 values following control of shivering. Clonidine causes decrease in heart rate and systolic blood pressure. The occurrence of bradycardia, hypotension, dry mouth, sedation is higher in clonidine group. The occurrence of nausea and vomiting are higher in Tramadol group compared to clonidine group. Clonidine is safer and effective alternative to Tramadol in controlling shivering in patients receiving spinal anesthesia for surgery.
Authors and Affiliations
Dr Sowmya M Jois
Clinicoetiological Profile and Management of Deep Vein Thrombosis (DVT) of Lower Limb
Background: Venous thrombosis of deep vein is a serious life threatening condition that may lead to sudden death in short term or to long term morbidity due to development of a post thrombotic limb and venous ulceration....
A Study Onserum Sodium and Potassium Level in Essential Hypertension
Background: Hypertension remains the most common readily identifiable and reversible risk factor for myocardial infarction, stroke, heart failure, atrial fibrillation, aortic dissection and peripheral arterial disease. B...
A Study to Determine the Clinico-Epidemiological Profile of CMV Seropositive Infants Admitted in a Tertiary Care Hospital
Background: Cytomegalovirus (CMV) infection is a common viral infection in new born and infants the clinical presentation of which is very variable. The objective was to study the clinical and epidemiological profile of...
Assessment of vitamin D status in children of Churu Region: An Observation Study
Background: Vitamin D is important for calcium and phosphorus metabolism. There are not many natural food items that contain vitamin D, therefore the amount of time in sunlight is the important source of vitamin D. Hence...
Pattern of Psychiatric Disorders in Postpartum Women attending Obstetrics and Gynaecology OPD of M.M.Medical College & Hospital, Kumarhatti, Solan(H.P.) India
Introduction: Pregnancy is the most beautiful and memorable time in a woman’s life. Pregnancy is considered as a period of increased vulnerability to psychiatric disorders. Psychiatric disorders during pregnancy are asso...