A Prospective Study of Evaluation of C - Reactive Protein in Patients of Ischemic Stroke
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 4
Abstract
Introduction: Evidences suggest that inflammation plays an important role in atherogenesis. Large numbers of studies have shown that C-reactive protein (CRP), an inflammatory marker, is associated with stroke severity and outcome. Data is limited which estimated the relationship of CRP in new patients of ischemic stroke. Study aimed to record C-reactive protein levels in patients with ischemic stroke and compare with different risk factor. Material and methods: Thirty new patients of ischemic stroke were compared with 30 patients without ischemic stroke in Department of Medicine and Neurology, G.R. Medical College, Gwalior from January 2016 to September 2017. Detailed history, clinical examination and investigation including C-reactive protein, blood glucose, CT scan and lipid profile were done in all the patients. Results: CRP was increased among cases compared to control group. CRP was significantly increased in patients with hypertension (75% and 33.33%; p=0.003), diabetes (60% and 54.54%; p<0.005), smoking (68.75% and 50%; p=0.049) in Cases compared to Control group respectively. CRP was increased more in patients with abnormal TC (61.53% and 44.44%; p=0.034), TG, (61.90% and 44.44%; p=0.021)), HDL (68.18% and 37.50%; p=0.012)) and LDL (28.57% and 35.29%; p=0.018)) in Cases compared to Control group. Conclusion: CRP was increased in new patients of ischemic stroke. CRP level on admission can be used to predict severity and early outcome. CRP was higher in patients with hypertension, smokers and patients with abnormal lipid levels.
Authors and Affiliations
Narayan Prasad Majhi, Sushma Trikha, Dinesh Udeniya, O P Jatav, Neelima Singh, Rahul T Sarode
Keywords
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