A Rare Case of Cyclops Deformity from India
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 2
Abstract
Background: Cyclopia is a disorder characterized by failure of the embryonic prosencephalon to properly divide orbits of the eye into two cavities. Chromosomal aberrations or toxins can cause problems in the forebrain-dividing process. Its incidence is 1 in 13,000 live births. The nose is either missing or replaced with a non-functional form of proboscis. Most such cases are naturally aborted. Case: A 25 year old primigravida reported with date–size disparity (dates: 23+1, first trimester USG: 21+5, size: 16 weeks) and subsequent USG revealed a dead fetus. Patient gave history of low grade fever in the past. She was induced and expelled a dead fetus of 300 gms which showed features of cyclopia with a proboscis above the single eye. Chromosomal analyses, however could not be done as the fetus was partially macerated. To conclude, cyclopia is a rare disorder, incompatible with life, with a complex and multifactorial etiology.
Authors and Affiliations
Lavina Chaubey
Keywords
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