A retrospective comparative study of prednisolone use in antagonist co-treated assisted reproductive technology cycles for patients with good prognosis
Journal Title: Turkish Journal of Obstetrics and Gynecology - Year 2018, Vol 15, Issue 3
Abstract
Objective: To investigate the impact of peri-implantation prednisolone use and its duration in antagonist co-treated assisted reproductive technology (ART) cycles of patients with good prognosis. Materials and Methods: Infertile patients treated with gonadotropin-releasing hormone antagonist protocol between January 2010 and June 2013 were included. The patients in group A (n=196) received no prednisolone. The patients in groups B (n=397) and C (n=371) received 5 mg oral prednisolone daily, for 4 and 12 days following embryo transfer, respectively. The main outcome parameter was live birth rate. Results: The ages of the groups were 30.1±4.6, 31.5±4.5, and 30.9±4.7 years, respectively (p=0.163). There was no statistically significant difference between the groups regarding cycle characteristics. Implantation rates were 20.7%, 24.6%, and 23.8%, respectively (p=0.163). Miscarriage rates were 1.5%, 3.5%, and 3.2%, respectively (p=0.859). Live birth rates were 28.7%, 29.3%, and 32.8%, respectively (p=0.482). Conclusion: Empiric prednisolone administration during the peri-implantation period does not seem to have beneficial effects in ART cycles of patients with good prognosis.
Authors and Affiliations
Batuhan Özmen, Emre Göksan Pabuçcu, Yavuz Emre Şükür, Hasan Ulubaşoğlu, Can Ateş, Murat Sönmezer, Bülent Berker, Cem Somer Atabekoğlu
Keywords
Related Articles
- EP ID EP379368
- DOI 10.4274/tjod.12244
- Views 128
- Downloads 0
Diagnostic sign of intra uterine extra amniotic adhesions with 4D ultrasonography: Sheet on string
.
Endothelial cell leptin receptors, leptin and interleukin-8 in the pathogenesis of preeclampsia: An in-vitro study
Objective Dolaşımda artan leptin ve leptin reseptörü, endotel hücrelerinde proenflamatuvar sitokinlerin üretimini artırabilir ve endotel disfonksiyonuna neden olabilir. Bu çalışmada, preeklampside umbilikal kord endotely...
Increased nuchal translucency and pregnancy outcomes: experience of Başkent University Ankara Hospital
Objective: First trimester nuchal translucency (NT) measurement is considered to be an important tool in antenatal follow-up. This study aimed to evaluate the outcomes of pregnancies with increased NT at Başkent Universi...
Inhibitory kappa B alpha expression in endometriosis
.
Primitive neuroectodermal tumor of genital tract in hysterectomized patient: A case report
Primitive neuroectodermal tumors are high-grade malignant neoplasms. These are uncommon entities for the female genital tract. The treatment, management and follow-up period of Ewing’s tumors are not well-defined because...