A REVIEW ON BILAYER TABLETS
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2013, Vol 1, Issue 3
Abstract
Over the past 30 years stated that the expense and complications involved in marketing new drug entities have increased, with concomitant recognition of therapeutic advantages of controlled drug delivery, greater attention has been focused on development of sustained or controlled release drug delivery systems. Bilayer tablet is new era for the successful development of controlled release formulation along with various features to provide a way of successful drug delivery system. Controlled release dosage forms have been extensively used to improve therapy with several important drugs. Use of bilayer tablet is a very different aspect for anti-inflammatory and analgesic. Bi-layer tablet is suitable for sequential release of two drugs in combination, separate two incompatible substances and also for sustained release tablet in which one Layer is immediate release as initial dose and second layer is maintenance dose. Bilayer tablet is improved beneficial technology to overcome the shortcoming of the single layered tablet. In the case of bilayered tablets drug release can be rendered almost unidirectional if the drug can be incorporated in the upper nonadhesive layer its delivery occurs into the whole oral cavity.
Authors and Affiliations
Jaldhara S Patel*| Shree Krishna Institute of Pharmacy, Shankhalpur, Becharaji, Mehsana, India- 384210, Divya Thakkar| Shree Krishna Institute of Pharmacy, Shankhalpur, Becharaji, Mehsana, India- 384210, Kalpen N Patel| Shree Krishna Institute of Pharmacy, Shankhalpur, Becharaji, Mehsana, India- 384210, Ketan J Patel| Shree Krishna Institute of Pharmacy, Shankhalpur, Becharaji, Mehsana, India- 384210
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