A STUDY OF CARDIOVASCULAR RESPONSES TO AUTONOMIC NERVE FUNCTIONS IN RHEUMATOID ARTHRITIS
Journal Title: International Journal of Basic and Applied Physiology - Year 2018, Vol 7, Issue 1
Abstract
Autonomic Neuropathy, found to be a strong predictor of sudden cardiac death, has been reported variably in patients with Rheumatoid Arthritis. Material and method: The study was carried out on 30 patients of rheumatoid arthritis, 20 healthy individuals as control. Patients were divided into three groups. Diagnosis of Rheumatoid Arthritis was based on the criteria developed by American Rheumatic Association. Assessment of cardiovascular autonomic nerve functions was performed using cardiovascular reflex tests. The results were complied, compared with each other and a conclusion was drawn. Results: Out of 30 patients in the study group, 20 patients had no autonomic neuropathy while 2 had mild autonomic neuropathy, moderate autonomic neuropathy was seen in 5 patients while 3 patients had severe autonomic neuropathy. All our patients having evidence of autonomic neuropathy had duration of rheumatoid arthritis of six or more years. Statistical analysis was performed by SPSS version 20.0. For all tests, p<0.05 was considered significant. Conclusion: 33.33% patients had abnormal response to various cardiovascular autonomic nerve functions, 50% of which had symptoms of dysautonomia, 80% had evidence of peripheral neuropathy and all patients had duration of rheumatoid arthritis six or more years.
Authors and Affiliations
Ankur wadhwa, Rampure Dilip, Irshad Hussain Askari
Keywords
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