A study of effect of Vitamin D supplementation in Osteoarthritis patients
Journal Title: Surgical Update: International Journal of Surgery and Orthopedics - Year 2018, Vol 4, Issue 2
Abstract
Introduction: Osteoarthritis (OA) is the common cause of musculoskeletal disability and pain. Osteoarthritis (OA) is a chronic disease characterized by a loss of articular cartilage and changes of the subchondral bone. Lower levels of vitamin D were associated with greater knee pain, poor quadriceps function with poor physical function. Several studies have documented that vitamin D supplementation increases muscle strength, improve physical performance, and decreases risk of falls among older people with low level of serum vitamin D. Materials &Methods: This present study was conducted at the outpatient clinic of the Department of Orthopedics at Maheswara Medical College & Hospital, Sangareddy during a February–December 2017 study period.The inclusion criteria were that the participants had symptomatic knee OA and low vitamin D status (25(OH)D < 30 ng/mL). Results: Data were analyzed using SPSS Statistics version 22 (SPSS, Inc., Chicago, IL, USA). Comparisonof baseline vs. post-vitamin Dsupplementation data was performed by paired t-test. One-way repeated-measurement ANOVA was used to test the time differences in muscle strength and physical performance. A p-value less than 0.05 for differences and the values were considered to be statistically significant. Dominant grip strength (p = 0.01) and overall physical performance, such as gait speed (p < 0.001), TUGT (p < 0.001), STS (p < 0.001), and 6MWT (p < 0.001), significantly improved after vitamin. Conclusion: Nevertheless, vitamin D supplementation is a safe and inexpensive way to improve muscle strength and physical function in this population. Based on these findings, we recommend vitamin D supplementation in knee OA patients that have poor physical function.
Authors and Affiliations
J. Ashok Vardhan Reddy, Sridhar Garikapati
Keywords
Related Articles
- EP ID EP506006
- DOI 10.17511/ijoso.2018.i2.06.
- Views 147
- Downloads 0
A clinical study to predict the outcome of patients with hollow viscus perforation in a tertiary care hospital using manheim peritonitis index
Introduction: Since a longtime multiple effort are been put forwarded to design an effective scoring system as to predict the outcome as to mortality and morbidity of patients admitting to hospitals with hollow viscus pe...
A retrospective study of female breast cancer: Stage and age correlation
Background: With 1 million new cases in the world each year, breast cancer is the commonest malignancy in women and comprises 18% of all female cancers. At present carcinoma breast is the leading cancer in India and is c...
Stress and burnout among doctors
Occupational stress is increasingly faced by doctors. Upto some extent, stress improves performance but when excessive, it becomes harmful. Doctors have more stress related mental health problems than general population....
A case of primary actinomycosis and secondary eumycetoma in anterior abdomen wall – A case report
Actinomycosis of abdomen accounts to only 10-20%. We report a 58-year-old diabetic man who presented with abdomen pain and swelling for 10 days duration associated with fever. Abdominal computed tomography showed a large...
Clinico pathological study of right iliac fossa masses and their management
Aim: The present study aims to study causes, modes of presentation, investigations of choice and management of right iliac fossa masses. Materials and Methods: A prospective study was undertaken on 50 patients presenting...