A STUDY OF HIGH DOSE VERSUS LOW DOSE FUROSEMIDE THERAPY IN PATIENTS WITH ACUTE DECOMPENSATED HEART FAILURE
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 26
Abstract
BACKGROUND In cases of Acute Decompensated Heart Failure (ADHF) Loop diuretics are an important component of current treatment and are administered to approximately 90% of patients who are hospitalized with heart failure1 . Despite decades of clinical experience with these agents, there are few studies to guide their use. MATERIALS AND METHODS Total 60 patients included in the study (30 in each group), were randomized into two groups – High dose and Low dose furosemide therapy group. Following were considered as the end points, negative fluid balance at 24 hours after admission, duration of hospital stay, trend of serum electrolytes, clinical outcome (death and hospital re-admission). RESULTS We noticed that there was significant diuresis in the first 24 hours and shorter hospital stay in high dose diuretic group. There was no significant difference in serum sodium and potassium levels and hospital re-admission. There was significant difference in the renal parameters with transient elevation in serum urea and creatinine, seen in high dose group as compared to low dose group. CONCLUSION Both high dose and low dose diuretic modality of treatment have equal role in the management of ADHF. High dose diuretic strategy has been associated with shorter hospital stay and rapid improvement in clinical symptoms so, it might be effective diuretic strategy.
Authors and Affiliations
Rajkumar Gurulingayya Hiremath, Durgaprasad Mallappa Kabade, Prashant Kumar Malkiwodeyar, Ameet Vasanthrao Khatawkar, Jagdeesh Gangadhar Mahajanshettar, Ganeshgouda Majigoudra, Veeresh Basavaraj Hubballi
Keywords
Related Articles
- EP ID EP567161
- DOI 10.18410/jebmh/2018/414
- Views 94
- Downloads 0
A CLINICAL STUDY ON SURGICAL MANAGEMENT OF OLECRANON FRACTURES
BACKGROUND Olecranon fractures are one of the most commonly seen orthopaedic injuries in the emergency room. Fractures of the Olecranon process of the Ulna typically occurs as a result of a motor-vehicle or motorcycle ac...
ASSOCIATION BETWEEN SUBCLINICAL HYPOTHYROIDISM AND DIABETIC RETINOPATHY IN TYPE 2 DIABETIC PATIENTS
BACKGROUND Several studies have demonstrated an association between subclinical hypothyroidism and diabetic retinopathy with conflicting results. This study is aimed to find out if any such association exists as it may h...
OCULAR ISCHAEMIC SYNDROME- A CASE STUDY
PRESENTATION OF CASE 55 years old male presented to ophthalmology department in our hospital with the complaints of an insidious onset of gradually progressive visual loss and pain in right eye since 3 months. Left eye w...
CLINICAL PRESENTATION OF OCULAR BLUNT INJURIES IN A TERTIARY EYE CARE CENTRE IN SOUTH INDIA
BACKGROUND The firm belief that only a severe blow to the eye will affect the vision, often results in complacency and delay in reporting to the ophthalmologist. This study is to emphasize that trivial injuries uncared f...
COMPARATIVE STUDY OF 0.125% BUPIVACAINE HYDROCHLORIDE VERSUS 0.125% BUPIVACAINE HYDROCHLORIDE WITH 25 µgms FENTANYL CITRATE FOR EPIDURAL ANALGESIA IN LABOUR
BACKGROUND Labour pains are said to be very intense for many women. They may adversely affect both mother and foetus. A variety of techniques are available to offer labour analgesia. Of all techniques, continuous epidura...