A study of multidrug resistant acinatobacter species at tertiary health care center
Journal Title: MedPulse -International Medical Journal - Year 2016, Vol 3, Issue 5
Abstract
Introduction: Acinetobacterbaumannii is an opportunistic pathogen that is frequently involved in outbreaks of infection occurring mostly in intensive care units Aims and Objectives: To Study Multidrug resistant Acinatobacter Species at Tertiary health care center. Methodology: This was a Cross-sectional study carried out in Microbiology Department at tertiary health care center during one year period from January 2014-2015. All samples were screened for the Acinatobacterand those samples positive were included into study. Total 96 samples were included into study. The statistical analysis done by Chi-square test. Result: In our study we have found that The majority of the Patients were from the age group of 20—40 years 39.58% followed by 40—60 years-25.00%; > 60 years-19.791% ;< 5 years-12.5%; 5—20 years-3.125%. Majority of the MDR isolates were from Urology-100%followed by; ICU-90.63%;General Surgery-89.48%Orthopedics-80.00%; Obstetrics and Gynecology;78.57%; Out patients-63.64%.This observed difference is statistically significant (p< 0.0003; x2 =29.39, df=8).The majority of the MDR isolates were from ET aspirate-(94.74%) followed by Pus-(84.22%);Blood-(83.33%); Sputum; (75.00%); Urine-(52.94%); Others-(50.00%). This observed difference is statistically significant (P<0.05, X2 = 13.53, df= 6). The majority of the antibiotic resistance pattern of MDR and non-MDR Acinetobacterisolates to Gentamicin-98.55% followed by Amikacin-98.24%; Co- trimoxazole-97.01%; Imipenem-95.45%; Piperacillin –tazobactam-94.11%; Ciprofloxacin-93.67%; Ceftazidime-93.67%; Ampicillin-80.43%; Amoxycillin –clabulanic acid-88.09%. This observed difference is statistically significant (P<0.0004,X2= 28.72 df=8). Conclusion: In our study we have found that The majority of the Patients were from the age group of 20—40 years, Majority of the MDR isolates were from Urology, The majority of the MDR isolates were from ET aspirate, The majority of the antibiotic resistance pattern of MDR and non-MDR Acinetobacterisolates to Gentamicin, followed by Amikacin, Co- trimoxazole, Imipenem-Piperacillin –tazobactam.
Authors and Affiliations
Ravindra S Mohite, S A Gadgil, Santosh S Patil, Dhanshree P Inamdar, Pradnya A Jadhav
Keywords
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