A study of prevalence of non-alcoholic fatty liver disease in type 2 Diabetes Mellitus
Journal Title: Panacea Journal of Medical Sciences - Year 2016, Vol 6, Issue 3
Abstract
Nonalcoholic fatty liver disease (NAFLD) is one of the common causes of chronic liver disease worldwide and is an emerging important cause of liver disease in India. In the general Indian population, the prevalence of NAFLD is approximately 9- 30% but much higher estimates are reported in obese and patients with type 2 diabetes mellitus. Total of 185 diabetic and 105 non-diabetic patients were randomly selected from diabetic and medicine OPD. After taking informed consent, all patients undergone history, examination and routine laboratory investigations, LFT, lipid profile, HbA1c, serum ferritin, C-reactive protein and USG. The results of cases and control were compared with unpaired t -test and p value <.05 was considered significant. The study group (n=185) was divided into a NAFLD group (n=102) and a non-NAFLD group (n=83) and nondiabetic control (n=105). The prevalence of NAFLD in DM was 55.68% and in non-diabetic was 20%. The NAFLD was significantly associated with high BMI, waist circumference and waist hip ratio, higher HbA1c, higher triglyceride levels, hypercholesterolemia, low HDL levels. Serum CRP level (p<0.00001) and serum ferritin level (p<0.0001) were significantly high in NAFLD patients with DM-2. This study showed that patients with central obesity, Poor Glycemic control and dyslipidemia are at increased risk of developing NAFLD. Serum ferritin and Serum CRP could be good noninvasive marker for screening of NAFLD in asymptomatic patients.
Authors and Affiliations
Kuldeep Chandel, Sandeep Kumar, Mahak Lamba
Keywords
Related Articles
- EP ID EP241796
- DOI -
- Views 94
- Downloads 0
Preoperative Magnetic Resonance evaluation of perineal endometriosis in episiotomy scar with anal sphincter involvement
Perineal endometriosis in episiotomy scar with anal sphincter involvement is an infrequent occurrence. After six months follow-up, there were no complications reported by faecal incontinence. Endometriosis is defined as...
A case of primary Eyelid Tuberculosis: A rare entity
Ocular tuberculosis may affect virtually any intraocular tissue and ocular adnexa and usually manifest in the form of conjunctivitis, scleritis, episcleritis, corneal phlycten, interstitial keratitis, granulomatous uveit...
Acute tuberculosis thyroid abscess presenting with thyrotoxicosis
Tuberculosis of the thyroid gland is a rare entity even in countries like India where tuberculosis is endemic. The patients may present with thyroid swelling, inflammation and very rarely thyroid dysfunction. Caseous nec...
Menstrual Hygiene: Knowledge and Practice among Adolescent School Girls
Menstruation is generally considered as unclean in the Indian society. Isolation of the menstruating girls and restrictions being imposed on them in the family, have reinforced a negative attitude towards this phenomenon...
Chronic Progressive External Ophthalmoplegia(CPEO): A not so rare mitochondrial myopathy
Mitochondria myopathies have a variable clinical presentation and CPEO(chronic progressive external ophthalmoplegia) is the hallmark which should alert the clinician to this diagnosis. Herein we report a-40-year old lady...