A study of renal functions in asphyxiated term newborns

Abstract

Introduction: Hypoxia and ischemia can cause damage to almost every tissue and organ in the body. Birth asphyxia is the most important cause of renal damage in term infants. This study was performed to evaluate the renal functions and to compare them with various grades of birth asphyxia in term newborns. This was also compared with levels in healthy term newborns. Methods: The present study was conducted at the Special Care Neonatal Unit of Mahila Chikitsalaya, SMS Medical College, Jaipur. It was a hospital based comparative analysis conducted from October 2015 to September 2016. It included 100 consecutive term neonates who suffered asphyxia at birth as cases and 50 consecutive healthy term newborns as controls. Results: Out of 100 asphyxiated cases, 20% had mild asphyxia (Apgar 6-7), 35% had moderate asphyxia (Apgar 4-5) and 45% had severe asphyxia (Apgar ≤3). Oliguria (Transient and Persistent) was more commonly seen in severely asphyxiated babies as compared to mild asphyxia (p=0.014) and moderate asphyxia (p=0.006). Blood urea and serum creatinine levels on Day 2 and Day 3 of life were significantly raised in severely asphyxiated babies as compared to mildly asphyxiated newborn. The serum electrolytes showed no significant difference among the three categories of asphyxia. Conclusion: Early estimation of blood urea, serum creatinine and monitoring of urine output should be done in all asphyxiated newborns so that the renal dysfunction can be detected earlier and appropriate measures can be taken in time to prevent renal damage in such newborns.

Authors and Affiliations

Saini R, Sehra RN, Verma S, Pansari VK, Nagaraj N, Yadav R

Keywords

Related Articles

Etiological profile and outcome of hypertransaminemia in children

Objectives: To study the causes of elevated transaminases in children and assess their outcome. Material and Methods: Retrospective study conducted at Kanchi Kamakoti CHILDS trust hospital, Chennai for 6 months. Medical...

Cognitive and developmental assessment between breast fed and mixed fed children: a cross sectional study

Introduction: The importance of breastfeeding for cognitive development has been researched widely over the past several decades and has been found to be associated with significantly higher scores for cognitive developm...

Prevalence of obstructive sleep apnea and central apnea in Overweight and Obese children

Introduction: Obstructive sleep disordered breathing with snoring, breathing through the mouth, apnea during sleep is very common among children. Many of these children outgrow the condition as the symptoms are very mild...

Langerhans cell sarcoma presenting as a mediastinal mass in a young infant: a case report

Langerhans Cell Sarcoma is an extremely rare disease. Its manifestations vary though skin, lymph-node and bone involvement are most commonly reported. It is an aggressive disease with a poor outcome. We report a six-week...

Rapidly progressing juvenile scleroderma: A case report

Juvenile Scleroderma encompasses a range of conditions unified by the presence of fibrosis of the skin. Juvenile scleroderma is of two major types: Juvenile localized scleroderma and Juvenile Systemic sclerosis. Juvenile...

Download PDF file
  • EP ID EP281896
  • DOI 10.17511/ijpr.2017.06.03.
  • Views 146
  • Downloads 0

How To Cite

Saini R, Sehra RN, Verma S, Pansari VK, Nagaraj N, Yadav R (2017). A study of renal functions in asphyxiated term newborns. Pediatric Review: International Journal of Pediatric Research, 4(6), 363-369. https://www.europub.co.uk/articles/-A-281896