A STUDY OF RENAL TUMOURS FOR A PERIOD OF 5 YEARS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 20
Abstract
BACKGROUND Cancer of the kidney amounts to 2 % of the total human cancer burden with approximately 1,90, 000 new cases diagnosed each year. They occur in all regions of the world with a higher incidence in developed countries. Etiological factors include environmental carcinogens (tobacco smoking) and life style factors, in particular obesity. Although renal tumours can be completely removed surgically, haematogenous metastases are frequent and may occur at an early stage of the disease. To understand the incidence of various renal tumours in relation to age, sex, location and frequency, a study was taken up for a period of 5 years. Histopathological study was carried out at Department of Pathology, Andhra Medical College, Visakhapatnam on the nephrectomy specimens received from King George Hospital. METHODS The present observational study is carried out in the department of pathology, Andhra Medical College. The material for the study included nephrectomy specimens received from surgical departments of King George Hospital. The relevant clinical history and data were taken in a prescribed proforma. The tissue blocks were prepared, stained with Haematoxylin and Eosin stains, and special stains like PAS, Van-Gieson and reticulin. IHC studies were done for relevant tumours. Our study included 55 nephrectomy specimens with tumours which were classified according to UICC/ TNM classification. RESULTS In the present study, the total number of nephrectomy specimens received were 90. Out of these specimens, 55 were removed for tumours either benign or malignant and the remaining 35 showed non-neoplastic conditions like hydronephrosis, chronic pyelonephritis, tuberculosis pyelonephritis and calculi. The incidence of tumours is found to be high in males compared to females in both the age groups. CONCLUSIONS Among the adult renal tumours, RCC was the most common malignancy observed. Majority of the tumours occurred in the fifth and sixth decades. As there is a significant difference in the outcome for different histological subtypes of RCC, subtyping was done. Clear cell RCC was the most common type observed and the results correlated with literature.
Authors and Affiliations
Satyasri Karri, Kartheek B. V. S
Keywords
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- EP ID EP617698
- DOI 10.14260/jemds/2019/355
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