A Study of Stress Induced Biochemical Changes In Pregnancy
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 4
Abstract
Aim:- To assess the risk of stress induced biochemical changes in pregnancy in view of their significant impact in developing diabetes and coronary heart disease through metabolic syndrome. Materials and Methods:- 15 cases of Primis in first trimester. 15 cases of Primis in third trimester with normal blood pressure. 15 cases of Primis in third trimester with PIH. Fasting blood glucose,Serum total proteins, Serum total triglycerides,Serum total cholesterol, Serum HDLCholesterol and Serum Ceruloplasmin were estimated. Results:- There was increase in levels of fasting glucose, total triglycerides, total cholesterol and ceruloplasmin and decrease in levels of HDL and total proteins as the pregnancy is progressing with further exaggeration in PIH.The change in normal pregnancy is serum hypertriglyceridaemia which may be as high as two to three folds in third trimester over the levels in non pregnant women.A significant decrease in HDL levels were observed in pre-eclamptic pregnant women.Plasma ceruloplasmin (CP) activity increased significantly (p<0.05) as pregnancy progressed.There was 3.60 fold increase in risk of pre-eclampsia among women with total cholesterol > 205mg / dl and 4.15 fold increase in risk of pre-eclampsia among women with triglycerides > 133mg /dl. Conclusion:- The present study concludes that pregnancy is a stressful condition resulting in varied biochemical changes. These changes are exaggerated when pregnant women have associated hypertension which is a risk factor of metabolic syndrome and they are possibly prone to diseases like diabetes mellitus, coronary artery diseases and stroke.
Authors and Affiliations
Dr. Mohana Lakshmi Jonnadula, Dr. Sireesha Maraju
Keywords
Related Articles
- EP ID EP594780
- DOI 10.9790/0853-1604070106.
- Views 83
- Downloads 0
A Study on the Clinical Profile of Patients with Ulcerative Colitis Attending a Tertiary Care Hospital in Central Kerala
Ulcerative colitis is a chronic disease of the bowel that results in inflammation and ulceration of the colon and rectum. It presents with loose stools mixed with mucous and blood. The exact etiology is unknown. The fact...
Clinical Profile and Visual Outcome of Ocular Injuries in a Tertiary Hospital in Northern India
Aim: To identify the various types of ocular injury presenting in a tertiary hospital in northern India..Material & Methods: Hospital-based, retrospective study conducted over a period of one year. A total of 100 patient...
Significance of Blood Microvessel Density Quantitation in Breast Carcinoma
Background: Metastasis is the leading cause of mortality in patients diagnosed with breast cancer. The common pathways of cancer cell dissemination are via the lymphatics and the bloodstreams. Objective: The aim of the p...
Etiological Analysis of Late Onset Epilepsy at R.I.M.S, Ranchi, Jharkhand, India
Introduction: Epilepsy describes a condition in which a person has recurrent seizures due to chronic underlying process. Epilepsy refers to a clinical phenomenon than a single disease entity, since there are many forms a...
Does Serum Testosterone Levels in Postmenopausal Women Have An Effect on Developing Carcinoma Breast: A Case Control Study
Large prospective cohort studies have shown that high levels of oestrogen in postmenopausal women increases mammary proliferation and is associated with an increased risk of developing breast carcinoma. However, there is...