A STUDY ON CARVEDILOL VERSUS METOPROLOL IN THE MANAGEMENT OF ATRIAL FIBRILLATION IN POST OPERATIVE CORONARY ARTERY BYPASS GRAFT SURGERY PATIENTS
Journal Title: International Journal of Pharmaceutical Sciences and Drug Research - Year 2018, Vol 10, Issue 4
Abstract
The objective of the present study is to analyse the effectiveness of carvedilol and metoprolol in the management of atrial fibrillation in post operative coronary artery bypass graft surgery patients. Atrial fibrillation occurs frequently soon after coronary artery bypass grafting and often results in increased mortality and morbidity. The incidence of post operative atrial fibrillation actually varies from 11% to 40% despite of the surgical technique and current guidelines recommend beta blockers as a medication for the prevention of atrial fibrillation after coronary artery bypass graft surgery. A prospective observational study was conducted on 100 subjects considering the inclusion and exclusion criteria and they were classified into carvedilol and metoprolol group. Heart rate was chosen as the primary parameter and statistical analysis was performed using student‘t’ test (p<0.05). There was a statistically significant decrease in the heart rate after therapy for both metoprolol and carvedilol but the difference in the effectiveness between carvedilol and metoprolol could not be significantly identified.
Authors and Affiliations
Prudence A Rodrigues, P R Murugesan, Anjana Balakrishnan, Megha Binoy, Jithin Titus Jacob
Keywords
Related Articles
- EP ID EP618423
- DOI 10.25004/IJPSDR.2018.100410
- Views 92
- Downloads 0
A NEW QUANTITATIVE ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE ANALYSIS OF BOCEPREVIR IN BULK AND MARKETED FORMULATION
A simple, precise and accurate RP-HPLC technique was developed and the developed method was validated for the regular analysis of Boceprevir. Chromatographic analysis was performed by selecting X-Terra ODS ( C18) column...
PREPARATION, BIODEGRADATION OF COCONUT OIL DRIVEN CHEMICALLY MODIFIED BOVINE SERUM ALBUMIN MICROPARTICLES OF ENCAPSULATED CICER ARIETINUM AMYLASE AND STUDY OF THEIR APPLICATION IN WASHING DETERGENTS
In present work, Cicer arietinum amylase was encapsulated by emulsification through covalent coupling by glutaraldehyde into chemically modified bovine serum albumin. Biodegradation of coconut oil driven emulsified bovin...
Detection of Biofilm Producers Causing Otitis Media: A Comparative Analysis of the Three Major Methods
Otitis media is the infection of the middle ear, caused as a result of the infection of the fluid built up in the tympanic cavity, mainly by bacteria even though viral and fungal otitis media has been reported. The bacte...
IN VITRO STUDIES ON THE EFFECT OF PROSOPIS CINERARIA ON THE MOTILITY AND ACETYLCHOLINESTERASE OF COTYLOPHORON COTYLOPHORUM
Paramphistomosis caused by the paramphistome Cotylophoron cotylophorum constitute a major group of disease in domestic ruminants. Chemical control of helminths coupled with improved management has important worm control...
BIOLOGICALLY ACTIVE TRITERPENES FROM EUGENIA PISIFORMIS CAMBESS. (MYRTACEAE)
In Brazil, Eugenia pisiformis, which belongs to botanical family Myrtaceae occurs in the states of Rio de Janeiro, Espírito Santo, Maranhão and Bahia. A specimen of E. pisiformis collected in Itatiaia National Park, Stat...