A Study on Management of Comorbidity and Complications In Liver Cirrhosis Patients
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2018, Vol 8, Issue 4
Abstract
Objectives: The main objective is to study on management of comorbidity and complications in liver cirrhosis patients, to study the severity of liver cirrhosis at the time of admission and to identify the risk factors and complications of liver cirrhosis in various populations. Methods: A prospective observational study has been done in limited period of 1 year in inpatient department of gastroenterology and general medicine. We have excluded the patients who are non-cooperative and receiving less than 24hrs of emergency care. We have included the patients who are admitted in inpatient department of gastroenterology and general medicine and the cases with demographic details and with or without social habits. Results and Conclusion: In this study we found that male patients were 91out of 122 cases and were more prone to liver disease as alcohol is the main risk factor where alcoholic patients were 79 out 122 cases with 64.75%.The Pantoprazole PDD was 47.5 and ratio between PDD:DDD (47.5:40) was 1.1, Octreotide PDD was 0.171 and ratio between PDD:DDD (0.171:0.7) was 0.244, Ciprofloxacin PDD was 1000mg and ratio between PDD:DDD (1000:1000) was 1, Furosemide PDD was 49.33 and the ratio between PDD:DDD (49.33:40) was 1.23, PropanololPDD was 39.41 and the ratio between PDD:DDD (39.41:160) was 0.24, Metoclopramide PDD was 20.12 and the ratio between PDD:DDD (20.12:30) was 0.66, Ketorolac PDD was 60 and the ratio between PDD:DDD (60:30) was 2, Tramadol PDD was 32.57 and the ratio between PDD:DDD (328.57:300) was 1.09, Lactulose PDD was 523.5 and the ratio between PDD:DDD (523.5:670) was 0.78, Ranitidine PDD was 130 and the ratio between PDD:DDD (130:300 ) was 0.43, Hyoscinebutylbromide PDD was 96 and the ratio between PDD:DDD (96:100) was 0.96. The main complications in liver cirrhosis was found to be portal hypertension 35.94% and ascites 20.2% out of 122 cases. Conclusion: The complications of liver cirrhosis like portal hypertension and ascites are more common than other complications. Risk factors were common in males than females as alcohol is the established risk factor
Authors and Affiliations
Venkateshwarlu K1, K. Kowshik2, ,K. Anusha,S. Sourab, ,A. Ram Rushi
Keywords
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