A Study on Prevalence of Sickle Cell Disease among Pregnant Women and Its Outcome
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2017, Vol 2, Issue 4
Abstract
Background: Medical experts for many years have daunted the occurrence of pregnancy in homozygote sickle cell patients. This is because of associated high risk for mother and fetus. The aim of his study is to determine the prevalence and maternal and fetal outcome of pregnant mothers with sickle cell disease in maharani hospital, jagdalpur,C.G. Materials And Methods: this is a hospital based cross sectional study of all booked pregnant mothers who attended the antenatal clinic of the hospital from 2016 to 2017. The parameters extracted from the folders included :age ,hemoglobin genotype, full blood count , complications of pregnancy,APGAR score ,and birth weight. Results: A total of 180 cases were booked for antenatal care, 142patients (78.89%) were heterozygous (HbAs) and 38 cases (21.11%) were homozygous (HbSS). Age distribution of women ranged from 18 to 43 year of age with mean of 24.39+4.12 year in HbAs group and 23.47 +3.24 year in HbSS group. Out of 173 deliveries 84.39% were vaginal and 15.60% were LSCS.Cesarean section required in 17.99% of cases in HbAS and 5.88% of cases in HbSS group. In HbAS group 82.01% of cases delivered vaginally and 94.12% in HbSS. Out of 139 births in HbSS and 34 births in HbAS, intrauterine death seen in 39.47% and 9.15% cases respectively. Perinatal mortaliy was significantly higher in HbSS group compared to HbAS group 44.74% vs 16.2 %;(p<0.05%) CONCLUSION: It was found that women with sickle cell disease have a higher risk for maternal morbidity and perinataladverse outcomes when compared with carriers of sickle cell trait.
Authors and Affiliations
Dr. Sitalakshmi Vuppu
Keywords
Related Articles
- EP ID EP506867
- DOI -
- Views 134
- Downloads 0
Ewing’s Sarcoma of Right Lung in a 32 Years Old Male Patient
Ewing’s sarcoma is the second most common primary osseous malignancy in children and young adults.However, infrequently, it can arise outside the skeletal system; rarer still, it can originate within the lung parenchyma....
A Prospective Clinical Study of Anorectal Disease at M.G. Hospital Bhilwara Rajasthan
Background – Anorectal disorders include a diverse group of pathologic disorders that generate significant patient discomfort and disability.Methods- Hospital prospective based study conducted in...
HPV In Malignant and Potentially Malignant Lesions – A Brief Review
Oral Squamous Cell Carcinoma (OSCC) presents as the most common form of oral cancer. Many etiological factors have been attributed to cause the disease, of which tobacco and alcohol consumption are well established. Curr...
Occupational Health Assessment of Power-loom Industry Workers in Solapur City Somnath Kolgiri1, Dr. Rahul Hiremath2.
Introduction: The power-loom sector is one of the important but unorganized parts of the textile industry of India and mostly run by private firms and plays an important role in the country's economy, providing employmen...
A Review on Novel H2 Receptor Antagonists-Lafutidine
This paper reviews the remarkable impact of H2-receptor antagonists Lafutidine in ulcer disease. The development and the scientific rationale of these agents are presented, and efficacy and safety aspects in the short- a...