A Study to Compare the Effect of Intrathecal Midazolam and Nalbuphine as an Adjuvant to Bupivacaine for Infra-umbilical Surgeries
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2019, Vol 6, Issue 2
Abstract
Context: Since spinal anaesthesia provides analgesia for short time with local anaesthetics, many intrathecal adjuvants to local anaesthetic drugs have been addressed to augment the clinical efficiency and duration of anaesthesia intra & post operatively. Aims: To compare the efficacy of midazolam and nalbuphine as adjuvants in spinal anaesthesia in infra umbilical surgeries. Material and method: This study was conducted on 50 patients aged 18 to 55 years ASA I and II, randomly divided in 2 groups by chit method undergoing elective infra-umbilical surgeries under spinal anaesthesia. Group BM received 0.5% bupivacaine heavy 3 ml, 2 mg preservative free midazolam made 3.5 ml with 0.9% normal saline and Group BN received 0.5% bupivacaine heavy 3 ml, preservative free 1 mg nalbuphine made 3.5 ml with NS. Onset & duration of sensory and motor blockade, hemodynamic changes, sedative effect, time of two segment regression, duration of analgesia and requirement of rescue analgesia, side effects/complications, if any were observed. Statistical analysis: Unpaired t-test was used for statistical analysis on IBM Statistical Package for Social Sciences version 21. p-value significant if <0.05. Results: Group BM provided short onset of sensory and motor block, longer duration of anaesthesia & post-operative analgesia, sedative effect and longer two-segment regression time as compare to group BN when used as adjuvant to hyperbaric bupivacaine. Conclusion: Midazolam is better adjuvant compare to nalbuphine when used intrathecally with bupivacaine 0.5% heavy provides longer duration of anaesthesia, sedation and post operative analgesia.
Authors and Affiliations
Sujay Thakkar
Keywords
Related Articles
- EP ID EP619484
- DOI 10.21088/ijaa.2349.8471.6219.45
- Views 99
- Downloads 0
Utilization of Ondansetron and Dexamethasone for Post-Operative Nausea and Vomiting (PONV) after Laparoscopic Cholecystectomy at Bhuj, Kutch, Gujarat: A Randomised Control Trial
Background and Aim: Postoperative nausea and vomiting still occur with unacceptable frequency and the description of it as the ‘Big Little Problem’ encapsulates much of the general perception. The incidence is quite high...
Effects of Hypercarbia on Spontaneous Ventilation in Short Laparoscopic Procedures
Context: Carbon dioxide is most commonly used to insufflate the abdominal cavity to facilitate short laparoscopic surgeries, where the real challenge lies in management of pathophysiological changes due to hypercarbia. A...
Intrathecal Dexmeditomedine as an Adjuvant with Bupivacaine for Spinal Anesthesia in Infra Umbilical Surgeries
Introduction: For lower abdominal and lower limb surgeries the neuraxial blockade is the preferred mode of anesthesia. In recent years, use of intrathecal adjuvants like dexmedetomidine has gained popularity with the aim...
Combined Psoas Compartment Block and Sciatic Nerve Block for Elective Lower Limb Surgeries
Introduction: Lower limb orthopedic interventions such as total hip arthroplasty (THA) and total knee arthroplasty (TKA) present a challenge to the anesthetist, as these procedures typically involve elderly patients ofte...
Right Ventricular Systolic Function in Off Pump Coronary Artery Bypass (OPCAB) and Its Measurement by Tricuspid Annular Plane Systolic Excursion
Background & Aim: Right ventricle function significantly decreases after coronary artery bypass surgery; as one of the likely causes, such a condition is attributed to the use of cardiopulmonary pump (CPB). Because nowad...