Accuracy of oral exfoliative cytology in Sudanese patients undergoing oral biopsy.
Journal Title: RSBO - Year 2011, Vol 8, Issue 3
Abstract
Introduction: Early detection of a premalignant or malignant oral lesions promises to improve the survival and the morbidity of patients suffering from these conditions. Oral exfoliative cytology (OEC) is a non-invasive method that is well accepted by the patient, and is therefore, suitable for screening at-risk population for early diagnosis of oral cancer. Objective: The purpose of this study is to investigate the value of OEC in the detection of oral premalignant and malignant lesions. Material and methods: In this hospital-based case-control study, cytological scrapes from buccal mucosa were obtained from 100 individuals, of whom 50 were patients with oral lesions ascertained as “cases” and 50 were clinically healthy volunteers ascertained as “controls”. All patients with oral lesions were also subjected to oral biopsy and histological examination. Results: Out of 50 cases studied, histopathology showed the presence of: Oral squamous cell carcinoma OSCC (n = 28), leukoplakia (n = 8), dysplasia (n = 3), and benign normal lesions (n = 11). In cytology, a specificity of 100%, sensitivity of 93% and accuracy of 92% were obtained for OSCC. Leukoplakia gave a specificity of 100%, a sensitivity of 87.5%, and an accuracy of 95%. Conclusion: Despite the small number of cases in this study, OEC is a useful method for detecting oral premalignant and malignant lesions. OEC can detect a number of pathological conditions that require management.
Authors and Affiliations
Ali Edris, Hussain Ahmed, Elneel Mohammed
Keywords
Related Articles
- EP ID EP155482
- DOI -
- Views 212
- Downloads 0
Temporomandibular joint dysfunction in children
Introduction and objective: The aim of this study was to review aspects related to the temporomandibular dysfunctions (TMD) in children,like etiology, diagnosis and treatment, emphasizing the importance of the correct di...
Single-cone obturation technique: a literature review
Introduction: The technique of single-cone obturation is a technique that uses only the master cone. There have been an increase in its use, especially by employing larger cones with larger taper sizes that best ma...
Tratamento da periimplantite: revisão da literatura
Introduction and objective: The aim of this study was to review in the literature the aim modalities of periimplantitis treatment. They were study the use of buccal antiseptics, antimicrobial treatment, open debridment,...
Dental pulp stem cells in endodontic research: a promising tool for tooth tissue engineering
Introduction: Millions of teeth are saved each year by root canal therapy. Although current treatment modalities offer high levels of success for many conditions, an ideal form of therapy might consist of regenerative ap...
Analysis of remaining tissue after using LAAXXESS® drill in flaring of cervical mesial canals of mandibular molars
Introduction and Objective: The objective of this study was to analyze, in vitro, the remaining tissue at the risk zone in the mesial canals of the mandibular molars after cervical flaring using LA AXXESS...