ACUTE CHANGES IN SERUM UREA, URIC ACID AND CREATININE IN HEALTHY YOUNG ADULTS AFTER MODERATE EXERCISE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 1
Abstract
BACKGROUND Effects of exercise on lipid profile of blood have been studied in many studies but studies to evaluate the exercise on blood indicators of renal functions are few. The aim of this study was to investigate the acute changes in serum urea, uric acid and creatinine in young healthy adults after single bout of moderate exercise. MATERIALS AND METHODS This uncontrolled clinical trial study was cleared by ethical committee of institution and total 79 untrained subjects (51 males, 28 females) of age group 18 to 35 yrs., participated in the study. Subjects were explained about study and gave written informed consent. Detailed information regarding dietary habits, any addiction, illness, medication was taken. After physical examination, blood samples were collected before exercise. Single bout of exercise by cyclometer for 30 minutes was done, and blood samples were taken after exercise along with physical examination. Serum levels of urea, uric acid and creatinine were analysed by auto analyser VITA LAB SELECTRA E. Data was collected and assessed by student ‘t’ test and p-value < 0.05 was taken as significant. RESULTS Pre and post exercise levels of urea (29.13 ± 4.73, 31.17 ± 4.75 mg/dl), uric acid (5.04 ± 0.94, 5.40 ± 1.01 mg/dl) and creatinine (0.82 ± 0.05, 0.84 ± 0.12) were measured. Statistical significance was observed between pre and post exercise levels of serum urea, uric acid and creatinine in males though no significant difference was noted in female subjects. CONCLUSION Further studies are needed to investigate the exercise induced changes in biochemical parameters of renal functions in larger groups.
Authors and Affiliations
Anubhav Dwivedi, Manju Lata Arya, Qazi Rais Ahmed
Keywords
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- EP ID EP553040
- DOI 10.14260/jemds/2019/16
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