Acute effects of air pollution on pulmonary function and exhaled nitric oxide in children in Shanghai
Journal Title: Shanghai Journal of Preventive Medicine - Year 2024, Vol 36, Issue 3
Abstract
Objective To investigate the acute effects of compound air pollution on children’s respiratory function.Methods Using panel group study design， 223 students in five classes of grade 4 from two primary schools （a， b） in Xuhui and Hongkou districts of Shanghai were randomly selected to measure pulmonary function and exhaled nitric oxide （FeNO）. The first three tests were carried out from May to June in 2020， and the fourth test was carried out from September to December in 2021. At the same time， the daily and hourly mean values of PM2.5， PM10， SO2， NO2， O3 and CO was collected from the nearby air quality monitoring points of the two schools during the same period， as well as meteorological monitoring data （temperature， humidity， wind speed and atmospheric pressure）. The linear mixed effect model was used to analyze the effects of air pollution on pulmonary function and respiratory inflammation in the summer.Results The results of single pollutant model showed that PM2.5， PM10， SO2 and NO2 were positively correlated with FeNO， and the effect was reflected in lag0， lag1 and lag3 （P<0.05）. PM2.5， PM10 and NO2 were negatively correlated with the changes of lung function FEF25%， FEF50%， FEF75%， FeF25%-75%， PEF， FVC， FEV1 and FEV1/FVC， and the effect was reflected in lag0 to lag3 days （P<0.05）. The results of the dual pollutant model showed that the concentration changes of SO2 and NO2 were significantly correlated with the decrease of FEV1 when combined with O3 or PM2.5 （P<0.01）， and the concentration changes of PM2.5 was significantly correlated with the increase of FeNO when O3， SO2 and NO2 were combined respectively （P<0.01）. The effects of the dual pollutant model were greater than the effect of PM2.5 single pollutant model.Conclusion The health effects of different air pollutants on children’s respiratory tract function indexes in summer are different. The combined effects of two pollutants on the lung function of children increased to different degrees. Although air pollution is light in summer， it still has an impact on children’s respiratory tract function index and inflammation index， and the combined effect of dual pollutants is more significant than that of single pollutant.
Authors and Affiliations
GAO Jianhui,WANG Yuhong,DING Yichen,SHI Lisha,XU Dong,LING Limin,PENG Li,ZHANG Lijun,
Keywords
Related Articles
- EP ID EP742018
- DOI -
- Views 52
- Downloads 0
Influencing factors of unprotected anal intercourse among Tianjin male homosexuals who used recreational drugs
<b>Objective:To explore the demographic characteristics and sexual behavior of men who have sex with men （MSM） in Tianjin， and to compare these aspects between recreational drug users and non-users. <b>Methods:This r...
Status and trend analysis of neuropsychological development of children aged 0â2 in Tongzhouï¼ Beijingï¼ 2017â2021
ObjectiveTo describe the neuropsychological development screening of 0â2 years in Tongzhou from 2017 to 2021 so as to understand the status and trend of developmental delay ï¼DDï¼.MethodsAnnual report data of 21 comm...
Reasons and achievement of Chinese dynamic zero-COVID-19 strategyâs consistency
COVID-19 has caused more than 600 million casesï¼ more than 6 million death and mortality of 1.24% worldwide. One out of every six people caught COVID-19 at the 5th wave of expansionï¼ having a mortality of 15 per 10 t...
Prevalence and influencing factors of reduced visual acuity among young children in Changning District, Shanghai
Objective To analyze the prevalence of reduced visual acuity of young children in Changning district of Shanghai and to explore the influencing factors， so as to provide a reference basis for formulating prevention and...
Advantages of COVID-19 vaccine in the T cell immune response
Objective To illustrate the mechanism of COVID-19 vaccine in the T cell immune response.Methods Based on the characteristics of T cell and B cell immune response， we matched the data of incubation periods across the SAR...