Acute Renal Failure as Part of Multi-Organ Failure: How Long We Should Wait before We Intervene? A Dissection of Studies
Journal Title: Journal of Enam Meical College - Year 2015, Vol 5, Issue 1
Abstract
Mortality rate in multisystem organ failure (MOF) is very high. Acute renal failure is an important part of MOF. In this special feature article I have aimed to streamline the achievements of different studies on continuous renal replacement therapy (CRRT) for a fruitful outcome. For this I have gone for retrospective evaluation of the studies reached through PubMed, internet alert system of different journals, proceedings of conferences on CRRT and personal communication with the experts in this field. I have evaluated the outcome of studies to explore the causes of failure to achieve a positive result and to identify the positive gains of studies. Finally, I have compiled the positive gains to outline a new strategy for future study and greater achievement. The findings of evaluation led to the conclusion that while planning for initiation of CRRT, multiple strategies should be targeted. The strategy should involve early initiation of CRRT guided by new markers of acute kidney injury (AKI), continuous venovenous hemofiltration (CVVH) modality, optimum intensity (intensity should be adequate enough to improve hemodynamics within a targeted period), selection of an effective filter membrane. Elderly patients should be studied in a different group. Cardiac patients with AKI should not be studied in the same group along with the patients with sepsis.
Authors and Affiliations
Najib Mohammad
Keywords
Related Articles
- EP ID EP36219
- DOI https://doi.org/10.3329/jemc.v5i1.21496
- Views 356
- Downloads 0
Maternal Health Care Practices among Mothers of a Selected Slum in Dhaka City
Background: Bangladesh is a small South Asian country which became independent in 1971 after a bloody war. Rapid urbanisation in Bangladesh (26% of the 147.1 million inhabitants live in urban areas) is fuelling a growt...
A 25-Year-Old Female with Unusually Large Complex Odontoma in Mandibular Molar Area Associated with Unerupted Tooth
Odontomas are benign tumours of odontogenic origin consisting of different dental tissues. Usually they are tooth size or smaller, but occasionally complex variety can exhibit considerable growth. They are usually asym...
Fingerprint: A Unique and Reliable Method for Identification
Fingerprints have been the gold standard for personal identification within the forensic community for more than one hundred years. It is still universal in spite of discovery of DNA fingerprint. The science of fingerp...
Acute Limb Ischemia in a 95-year-old Female
plaques in aorta, mainly in the infrarenal segment, the aorta was patent up to its bifurcation. Aboveknee amputation was done on following day after admission with subsequent disarticulation. Acute limb ischemia is a...
A 16-Year-Old Female with Peutz-Jeghers Syndrome
Peutz-Jeghers syndrome is a rare autosomal dominant disorder of hamartomatous polyposis of the gastrointestinal tract, with pigmentation around lips and macules on the buccal mucosa that typically manifests itself as rec...