Adenomatous Polyposis of Gall Bladder: A Rare Presentation in HCV Positive Female
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2017, Vol 6, Issue 4
Abstract
Background: Gall bladder (GB) adenomatous polyps are uncommon and are usually an incidental finding. Infections serve as a fertile soil for gall bladder polyps. Risks for GB polyps are seen in patients with hepatitis B viral (HBV) infection with HBsAg serving as a risk factor. Hepatitis C viral (HCV) infection facilitates GB stone formation and the incidence is seen more in middle aged females. Case Description: Hereby, we present a case of 40 year old female presenting with long term intermittent abdominal pain. Patient was found to have, positive HCV serology (HCV genotype 3) with high viral load. USG and CT showed multiple gall bladder polyps. Histology revealed multiple adenomatous polyps of gall bladder with focally dysplastic epithelium. Final diagnosis of adenomatous polyp with dysplasia was given. Literature Review: Gall bladder polyps are usually single and a rare occurrence. The risk of malignancy in an adenomatous polyp increases in solitary and sessile polyps. The primary goal of management of Gall bladder polyp is to prevent the development of gall bladder adenocarcinoma. The literature is short of case reports where HCV infection has been associated with GB polyps. Clinical Significance: In our case, multiple GB polyps were seen in a HCV positive female. This association of multiple GB polyps with HCV infection is a rare association and to the best of our knowledge has not been previously reported in the literature.
Authors and Affiliations
Jyotsana Harit Gaur
Keywords
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- EP ID EP471185
- DOI 10.21088/ijprp.2278.148X.6417.30
- Views 67
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