Adult Attention-Deficit and Hyperactivity Disorder and Fibromyalgia: A Case-Control Study
Journal Title: Neuro – Open Journal - Year 2015, Vol 2, Issue 2
Abstract
Introduction: Fibromyalgia syndrome (FMS) is a disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory and mood issues. An association between attention deficit and fibromyalgia was reported. However, to our knowledge, there are few articles reporting an association between adult Attention Deficit Hyperactivity Disorder (ADHD) and FMS. We hypothesized that ADHD should be frequently associated with FMS. To confirm this hypothesis we conducted this study. Methods: Patients with Cognitive Complaint (CC) recruited from the membership of the Italian Hospital Medical Care Program in Argentina from 2009 to 2013 were classified as ADHD or without ADHD, and compared with Normal Controls (NC) about the presence of FMS. Adapted DSM-IV criteria for adult ADHD and validated to Spanish Wender Utah Rating Scale were used to identify individuals with adult ADHD. FMS was diagnosed according to Criteria Classification of Fibromyalgia of American College of Rheumatology of 1990. Analysis of categorical variables was carried out using chi-square. Mann-Whitney test was used for continuous variables. Statistical significance was P<0.05. Results: We identified 154 patients with ADHD, 71 NC, and 262 with CC without ADHD. Amongst ADHD cases, 37.7% were men, the median age was 72.5 years, in NC group, 40.8% were men with a mean age of 71.9, and in CC group, and 40% were men with a median age of 71.4 years. No significant differences in these variables between groups or in the years of education were found. Frequency of FMS was 24.7% in ADHD cases, 4.6% in CC group and 0% in NC. Prevalence of FMS in ADHD patients was significantly higher compared with other control groups (P<0.00001, 95% confidence interval extends from 0.0786 to 0.1330). Conclusion: In our sample, FMS is more prevalent in adult ADHD cases than in NC and CC patients as we expected. It should be done future studies to characterize the association of this disorders.
Authors and Affiliations
Golimstok Angel
Positron Emission Tomography Neuro-Imaging
Positron Emission Tomography (PET) is a powerful imaging technique exploring in vivo brain functions. Today PET is becoming an essential tool in specialist clinical neurology settings particularly for diagnosing Alzheime...
Audit of a Standard Operating Procedure to Prevent Wrong-Level Lumbar Spinal Surgery with Intra-Operative X-Ray
Introduction: One of the major errors that can be encountered by a spinal surgeon is operating at the wrong level/side. However, wrong-level spinal surgery is considered a ‘never-event’ and is under-reported. Many surgeo...
Endovascular treatment of Stroke: Historical Perspective
Effective acute ischemic stroke therapy hinges on rapid restoration of blood flow to the ischemic tissue. Since the National Institute of Neurological Diseases and Stroke r-tPA study,1 intravenous fibrinolytic therapy in...
Clinical Data Associated With the Therapeutic Response to Glatiramer Acetate in Multiple Sclerosis Patients
Background: The increasing appearance of new drugs is making more difficult the choice of treatment in multiple sclerosis. According to different criteria, between 20 to 50% of the patients with multiple sclerosis (MS) t...
Toxin-Induced Parkinson’s Disease Models
The Topic “Toxin-Induced Parkinson’s Disease Models’ includes articles on experimental neurotoxic chemicals models of Parkinson’s Disease (PD). The model toxicants with differing chemical structures recapitulate PD ownin...