Advances and ethics in research of early mammalian embryonic development
Journal Title: Biomedical Transformation - Year 2020, Vol 1, Issue 1
Abstract
The importance of early embryonic development in ensuring human health has long been recognized. Insights into the mechanisms of human early embryonic development can potentially contribute towards improving public health and reversing population aging, and promoting economic and social development. However, our knowledge of regulation networks that underpin human early embryonic development is far from complete due to technological and ethical constrains. Recently, incredible progress in scientific research on in vitro culture of mammalian embryos and embryoid technology represents a great opportunity in disclosing the mystery of human early embryonic development but also presents the toughest ethical challenges. Here we systematically review the major progress of research on early mammalian (rodent and primate) embryonic development, discuss the ethical debates about human embryo research, and lay out the future direction for the study of the early embryonic development regulation for both basic research and clinical application.
Authors and Affiliations
Wang Hongmei
Translational medicine and traditional Chinese medicine research practice
More and more scholars have paid attention to traditional Chinese medicine since the concept of translational medicine was introduced into this field. Most scholars believe that it is of great benefit to the inheritance...
Advances in the application of multi-omics and machine learning technologies in sepsis research
Sepsis is one of the major global health challenges, with its complex pathological mechanisms and multi -organ dysfunction posing serious threats to patient survival. In recent years, the combination of multiomics techno...
Research progress and prospects of bone defect therapy using stem cell-derived exosomes
Bone regeneration is a sophisticated, precisely controlled physiological process. In addition to bone metabolism balance under normal conditions, bone regeneration occurs also in bone repair process following bone damage...
Role and application of intestinal flora in human health
In the coevolutionary journey with humans, the complex and diverse human intestinal flora has evolved to regulate the human immune responses and affect the development of diseases. This immunomodulatory effect is closely...
Prognosis and influencing factors of 30 cases of malignant melanoma of nasal cavity and paranasal sinuses
Objective To investigate the clinical features of malignant melanoma of nasal cavity and paranasal sinuses (sinonasal malignant melanoma, SNMM) and its correlation with prognosis. Methods A retrospective analysis was con...