Advances in mono-nuclear macrophages in the pathogenesis of acute kidney injury
Journal Title: Biomedical Transformation - Year 2022, Vol 3, Issue 2
Abstract
Acute kidney injury (AKI) is a common life-threatening kidney disease with unclear etiology and mechanism. Mono-nuclear macrophages (MPCs) are the main inflammatory effector cells after kidney injury, which play an important role in the initiation, progress, and chronic transition of AKI, and might be a potential therapeutic target for AKI. Renal MPCs are highly heterogeneous in molecular phenotype, origin and cellular function. We will review the MPC heterogeneity and their roles in the pathogenesis of AKI.
Authors and Affiliations
Li Zehua, Yang Li
Keywords
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- EP ID EP766826
- DOI 10.12287/j.issn.2096-8965.20220203
- Views 12
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