AETIOLOGY AND EPIDEMIOLOGICAL PROFILE OF CORNEAL ULCERATION IN TERTIARY CARE CENTRE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 76
Abstract
BACKGROUND The epidemiology of corneal blindness is much complicated and encompasses a wide variety of inflammatory and infectious eye diseases that cause corneal scarring that ultimately leads to functional blindness. In addition, the prevalence of corneal disease varies from one population to another and from country to country. The purpose of this study was to study the epidemiology of corneal ulcer in a tertiary care centre and identify the various risk factors, predisposing factors in corneal ulcers and the microbial spectrum causing the ulcers. MATERIALS AND METHODS This descriptive study was conducted in a tertiary care hospital in patients attending Department of Ophthalmology, K. R. Hospital, Mysore Medical College and Research Institute, Mysore, in a period of 1 year from April 2016 to March 2017. Corneal epithelial loss with suppuration associated with signs of inflammation with or without hypopyon was taken as corneal ulcer. All patients diagnosed with corneal ulcer were included. Complete history, detailed ocular examination with risk factors were recorded. Corneal scrapings collected from the edge of the ulcer were processed for microbiological analysis at K. R. Hospital. RESULTS Total number of patients included in the study was 123, out of which there were 73 (59.35%) males and 50 (40.65%) females with male preponderance. The rural population (88.62%) was affected much more commonly than the urban (11.38%). Trauma was the most common predisposing factor leading to corneal ulcers (94.30%). Sugarcane/paddy stick injury (34.91%) being the most common mode of trauma. Streptococcus pneumoniae was the most commonly isolated Gram-positive bacterial organism representing 22 (41.51%) and Pseudomonas spp. was the most frequently occurring Gram-negative organism and it was isolated from 11 cultures (20.75%). Among 35 cases with pure fungal growths, fusarium was found commonest 21 (17.07%). CONCLUSION Infective keratitis being the leading cause for monocular blindness, early clinical suspicion, diagnostic laboratory procedures and appropriate timely therapy has tremendous role in reducing ocular morbidity
Authors and Affiliations
Hemalatha Krishnamurthy, Manjula Devi N, Satish K, Shyam S, Shreedevi Badagi, Sujatha Sujatha, Mohammed Abdul Khayoom, Chandresh Suthar
Keywords
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- EP ID EP267490
- DOI 10.14260/Jemds/2017/1185
- Views 93
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