Agreement between standard methods of Food hypersensitivity diagnostics IN CHILDREN
Journal Title: Астма и Аллергия - Year 2018, Vol 1, Issue 2
Abstract
The objective was to study agreement between standard methods of food hypersensitivity diagnostics. Materials and methods. 424 patients aged 26,3 (12,1; 54,25) months were included in the study. Methods included skin prick-test, specific IgE (sIgE) detection, oral provocation test (OPT). Results. Statistically significant difference was identified between age periods by results of the analysis of the anamnesis (Kruskal–Wallistest: H (4, N = 424) = 16,4; p = 0,003), OPT H (4, N = 196) = 29,5; p = 0,001) and its’ combination (H (4, N = 196) = 29,50; p = 0,001). Agreement between tests in patients aged up to 1 y.o. was unsatisfying. In children older than 1 y.o. moderate agreement was identified between sIgE detection and prick-test (κ = 0,5 (95% CІ = 0,4–0,59), sIgE and OPT (κ = 0,5 (95% CІ = 0,47–0,53). Conclusions. Standard tests of the diagnostics of the skin food hypersensitivity symptoms, especially in children up to 1 y.o., can not be used interchangeably. Key words: food hypersensitivity, children, prick-test, oral provocation test, Cohen’s kappa, agreement.
Authors and Affiliations
S. M. Nedelska, O. P. Pakholchuk
Keywords
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- EP ID EP395569
- DOI 10.31655/2307-3373-2018-2-7-11
- Views 145
- Downloads 0
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